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[Preprint]. 2024 May 3:2024.05.01.24306691. [Version 1] doi: 10.1101/2024.05.01.24306691

Evaluating a Large Language Model’s Ability to Answer Clinicians’ Requests for Evidence Summaries

Mallory N Blasingame, Taneya Y Koonce, Annette M Williams, Dario A Giuse, Jing Su, Poppy A Krump, Nunzia Bettinsoli Giuse
PMCID: PMC11092721  PMID: 38746273

Abstract

Objective

This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians’ gold-standard evidence syntheses.

Methods

Questions were extracted from an in-house database of clinical evidence requests previously answered by medical librarians. Questions with multiple parts were subdivided into individual topics. A standardized prompt was developed using the COSTAR framework. Librarians submitted each question into aiChat, an internally-managed chat tool using GPT-4, and recorded the responses. The summaries generated by aiChat were evaluated on whether they contained the critical elements used in the established gold-standard summary of the librarian. A subset of questions was randomly selected for verification of references provided by aiChat.

Results

Of the 216 evaluated questions, aiChat’s response was assessed as “correct” for 180 (83.3%) questions, “partially correct” for 35 (16.2%) questions, and “incorrect” for 1 (0.5%) question. No significant differences were observed in question ratings by question category (p=0.39). For a subset of 30% (n=66) of questions, 162 references were provided in the aiChat summaries, and 60 (37%) were confirmed as nonfabricated.

Conclusions

Overall, the performance of a generative AI tool was promising. However, many included references could not be independently verified, and attempts were not made to assess whether any additional concepts introduced by aiChat were factually accurate. Thus, we envision this being the first of a series of investigations designed to further our understanding of how current and future versions of generative AI can be used and integrated into medical librarians’ workflow.

Full Text Availability

The license terms selected by the author(s) for this preprint version do not permit archiving in PMC. The full text is available from the preprint server.


Articles from medRxiv are provided here courtesy of Cold Spring Harbor Laboratory Preprints

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