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Journal of Feline Medicine and Surgery logoLink to Journal of Feline Medicine and Surgery
. 2010 Oct 1;12(10):790–793. doi: 10.1016/j.jfms.2010.06.009

CD3+ and BLA.36+ cells do not occur in the epidermis and adnexal epithelia of normal skin from the dorsolateral trunk of cats

Michelle M Tranchina 1, Danny W Scott 2, Sean P McDonough 3
PMCID: PMC11135521  PMID: 20817525

Abstract

A small population of resident T-lymphocytes is present in the normal epidermis of humans, mice, and rats. However, resident epidermal lymphocytes have not been reported in the normal skin of the cat. Skin-biopsy specimens from the normal skin of the dorsolateral trunk from 30 cats were examined histologically and immunohistochemically for the presence of lymphocytes, CD3+ cells, and BLA.36+ cells in epidermis and adnexal epithelia. All examinations were negative. It appears that lymphocytes occur rarely, if at all, in the epidermis and adnexal epithelial of normal cat skin. Hence, the presence of lymphocytes in these structures should be considered abnormal.

Contributor Information

Michelle M. Tranchina, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA

Danny W. Scott, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA  shb3@cornell.edu

Sean P. McDonough, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA

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