Table 1. Inclusion and exclusion criteria.

RCT, randomized control trial

Inclusion criteria

·        Interventional studies only (either RCT or observational)

·        Sufficient reporting detail of all relevant variables including magnesium dose, form, and time length of administration

·        Standardized instruments to measure anxiety or sleep outcomes (or polysomnography in the case of sleep disorders)

·        Human studies only (all animal studies were excluded)

·        Inclusion not restricted by age of participant or type of magnesium salt

Exclusion criteria

·        Insufficient dose of magnesium, defined as ≤50 mg/12.5% of RDA for purposes of this review or unknown magnesium dose

·        Presence of >3 other potentially active compounds in the formulation

·        Manuscript language other than English