Table 1.

Demographic characteristics and comorbidities.

	Control, N = 14	Severe, N = 9	Critical, N = 21	P-value*
Age	52 (40, 60)	47 (47, 55)	48 (42, 65)	0.8
Gender				>0.9
female	6 (43 %)	3 (33 %)	7 (33 %)
male	8 (57 %)	6 (67 %)	14 (67 %)
Height	1.68 (1.54, 1.75)	1.67 (1.64, 1.68)	1.70 (1.60, 1.73)	0.9
Unknown	4	0	0
Weight	72 (62, 81)	82 (74, 85)	80 (75, 91)	0.14
Unknown	4	0	0
BMI categories				0.002
Normal weight	2 (14 %)	1 (11 %)	2 (9.5 %)
Obesity	0 (0 %)	5 (56 %)	11 (52 %)
Overweight	8 (57 %)	3 (33 %)	8 (38 %)
No data	4 (29 %)	0 (0 %)	0 (0 %)
Comorbidities
Obesity	1 (7.1 %)	0 (0 %)	8 (38 %)	0.031
DM2	1 (7.1 %)	1 (11 %)	6 (29 %)	0.3
Hypertension	1 (7.1 %)	3 (33 %)	9 (43 %)	0.066
Heart disease	0 (0 %)	0 (0 %)	1 (4.8 %)	>0.9
Renal insufficiency	0 (0 %)	0 (0 %)	1 (4.8 %)	>0.9
Immunosuppression	0 (0 %)	0 (0 %)	0 (0 %)
Asthma	1 (7.1 %)	1 (11 %)	0 (0 %)	0.3
COPD	0 (0 %)	0 (0 %)	0 (0 %)
HIV	0 (0 %)	0 (0 %)	0 (0 %)
GERD	2 (14 %)	1 (11 %)	0 (0 %)	0.2
Allergic rhinitis	0 (0 %)	2 (22 %)	0 (0 %)	0.038
Alcoholism	0 (0 %)	2 (22 %)	5 (24 %)	0.12
Smoking	0 (0 %)	1 (11 %)	7 (33 %)	0.031
Initial Antibiotic	0	8 (89 %)	15 (71 %)	<0.001
Days hospitalized	0 (0, 0)	11 (0, 16)	29 (13, 37)
Days onset sampling	0 (0, 0)	9 (7, 12)	10 (8, 14)

Median (IQR); n (%); *Kruskal-Wallis rank sum test; Fisher's exact test.

BMI Body Mass Index, DM2 Diabetes Mellitus Type 2, GERD Gastroesophageal reflux disease.