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. 1999 Jan 30;318(7179):331. doi: 10.1136/bmj.318.7179.331

Intensive cognitive behaviour therapy for chronic schizophrenia

Specific effect of cognitive behaviour therapy for schizophrenia is not proved

David Curtis 1
PMCID: PMC1114795  PMID: 9924074

Editor—Tarrier et al’s randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia seems to show that cognitive behaviour therapy offers advantages over routine care alone. It is not clear, however, that the patients receiving cognitive behaviour therapy did better than a third group, which received non-specific supportive counselling. The outcomes in this group were intermediate between those for the cognitive behaviour therapy and routine care groups and apparently did not differ significantly from either, although the paper is not as clear as it could be on this point.

This study provides some evidence that the course of schizophrenia can be improved by psychological support, but we cannot conclude that cognitive behaviour therapy exerts any specific effect. This is important for two reasons. Firstly, understanding what interventions affect the course of the illness may help us to understand the pathological mechanisms involved. Secondly, cognitive behaviour therapy is likely to be substantially more expensive than supportive counselling. Many schizophrenic patients already receive supportive counselling as part of their routine care, perhaps as part of sessions with a key worker at a day centre or in their supported accommodation. Finally, the authors did not mention the fact that of the patients available for follow up, 8 of 32 receiving cognitive behaviour therapy dropped out or refused follow up while only 3 of 24 receiving supportive counselling did so. This difference is not significant, but it is as noteworthy as several of the results that the authors do draw attention to.

References

  • 1.Tarrier N, Yusupoff L, Kinney C, McCarthy E, Gledhill A, Haddock G, et al. Randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia. BMJ. 1998;317:303–307. doi: 10.1136/bmj.317.7154.303. . (1 August.) [DOI] [PMC free article] [PubMed] [Google Scholar]
BMJ. 1999 Jan 30;318(7179):331.

Author’s reply

Nicholas Tarrier 1

Editor—As Curtis says, the direction of improvement reported in our trial was indicative of patients receiving cognitive behaviour therapy doing better than those receiving supportive counselling, who in turn did better than those given routine care alone in the intention to treat analysis. The significant differences, however, were for cognitive behaviour therapy over routine care in post hoc tests.

In a more detailed analysis of symptom types in patients who received the full treatment protocol, there were considerable differences between cognitive behaviour therapy and supportive counselling, mainly in greater improvement of hallucinations in those who received cognitive behaviour therapy. Furthermore, in the study supportive counselling had the same “therapy envelope” as cognitive behaviour therapy—that is, 20 hourly sessions delivered twice a week. I would be sceptical that this level of intervention currently takes place as routine care delivered by key workers, as Curtis suggests. My colleagues and I are currently investigating the effectiveness of supportive counselling more fully in a multisite trial comparing cognitive behaviour therapy, supportive counselling, and routine care alone in 320 acutely ill patients with schizophrenia of recent onset.

Reasons why patients drop out of treatment are always of interest, and we have reported the reasons that patients gave for dropping out.1-1 There was no evidence that the relatively small and non-significant difference between groups in the number of patients who dropped out was related to the type of treatment to which they were allocated.

References

  • 1-1.Tarrier N, Yusupoff L, McCarthy E, Kinney C, Wittkowski A. Some reasons why patients suffering from chronic schizophrenia fail to continue in psychological treatment. Behav Cogn Psychother. 1998;26:177–181. [Google Scholar]

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