Abstract.
A variety of viral-based and immune cell therapies have been proposed for use in the treatment of cancer. One possible approach to improve the effectiveness of these biological agents may be to combine them such that we can take advantage of natural immune cell-pathogen relationships. Here we discuss these potential approaches with particular emphasis on the use of immune cells as carrier vehicles to deliver viral therapies to the tumor.
Keywords. Oncolytic virus, immunotherapy, cancer therapy, imaging
Footnotes
Received 15 December 2006; received after revision 28 January 2007; accepted 5 March 2007