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. Author manuscript; available in PMC: 2024 Jun 6.
Published in final edited form as: Resuscitation. 2023 Feb 16;186:109735. doi: 10.1016/j.resuscitation.2023.109735

Figure 3: Post-ROSC Hemodynamics and Left Ventricular Function in Swine Resuscitated with T3np, T3np+PCR, and EPI After Cardiac Arrest.

Figure 3:

Hemodynamic and echocardiographic parameters were similar among treatment groups prior to cardiac arrest and were generally similar throughout the post-resuscitation period. Notable differences among groups were observed only at the 15-minute post-ROSC timepoint, as EPI-treated animals exhibited an elevated heart rate, LV dP/dtmax, and LV ejection fraction relative to T3np-treated animals. Values are mean±SEM. *p<0.05: T3np vs. EPI; †p<0.05: T3np+PCr vs. EPI. LV = left ventricular; ROSC = return of spontaneous circulation; T3np = triiodothyronine nanoparticles; T3np+PCr = triiodothyronine nanoparticles with encapsulated phosphocreatine.