In the published article, there was an error in Tables 1, 2 as published. This error pertains to the continuous data presented in the primary manuscript. The median values and interquartile ranges were incorrect. It is crucial to note that the primary endpoint (mortality), figures, and all but one provided p-values (Table 1—Hypertension: p = 0.4740 was previously displayed and is incorrect. The correct p-value is 0.3092) remain unaffected, as they either do not involve continuous data or were calculated independently. The corrected Tables 1, 2 and its caption appear below.
Table 1.
Patients characteristics and endpoints by ICU mobility scale under V-V ECMO.
| Baseline characteristics | Total (n = 343) | ICU mobility scale < 2 (n = 281) | ICU mobility scale ≥2 (n = 62) | p-value |
|---|---|---|---|---|
| Percentage of patients | 100 | 82 | 18 | |
| Age | 55 (45–64) | 55 (45–64) | 57 (42–63) | 0.9014a |
| Female gender | 108 (31.5%) | 90 (32%) | 18 (29%) | 0.7628b |
| BMI | 25.1 (23.6–30.2) | 24.8 (23.5–30.2) | 26.8 (23.8–30.6) | 0.2358a |
| Preexisting conditions | ||||
| Hypercholesterolemia | 41 (12%) | 34 (12.1%) | 7 (11.3%) | 0.9999b |
| Nicotine use disorder | 109 (31.8%) | 89 (31.7%) | 20 (32.3%) | 0.9999b |
| Coronary heart disease | 37 (10.8%) | 29 (10.3%) | 8 (12.9%) | 0.5058b |
| Hypertension | 124 (36.2%) | 98 (34.9%) | 26 (41.9%) | 0.3092b |
| Liver cirrhosis or chronic hepatitis | 21 (6.1%) | 20 (7.1%) | 1 (1.6%) | 0.1425b |
| Chronic kidney disease | 23 (6.7%) | 20 (7.1%) | 3 (4.8%) | 0.7788b |
| Diabetes mellitus | 49 (14.3%) | 40 (14.2%) | 9 (14.5%) | 0.9999b |
| Oncological disorders | 59 (17.2%) | 52 (18.5%) | 7 (11.3%) | 0.1972b |
| Immunodeficiency | 93 (27.1%) | 83 (29.5%) | 10 (16.1%) | 0.0394 b |
| Chronic lung disease | 97 (28.3%) | 79 (28.1%) | 18 (29%) | 0.8772b |
| CPR within 48 h before EMCO | 32 (9.3%) | 30 (10.7%) | 2 (3.2%) | 0.0890 b |
| Respiratory situation before ECMO | ||||
| Horowitz index | 70 (58–93) | 71 (59–96) | 64 (51–79) | 0.0038 a |
| pO2-arterial (mmHg) | 65 (58–75) | 66 (58–76) | 62 (47–73) | 0.0173 a |
| FiO2 | 1.0 (0.8–1.0) | 1 (0.8–1) | 1 (0.9–1) | 0.1662a |
| pCO2-arterial (mmHg) | 56 (46–73) | 57 (46–73) | 50 (43–72) | 0.2392a |
| pH–arterial | 7.3 (7.2–7.3) | 7.2 (7.2–7.3) | 7.3 (7.2–7.4) | 0.0002 a |
| Peak inspiratory pressure ≥42 cm H2O | 33 (9.6%) | 30 (10.7%) | 3 (4.8%) | 0.2325b |
| ICU stay | ||||
| Duration of ICU stay from ECMO d1 (d) | 13.7 (8.7–26.8) | 12.9 (7.3–21.5) | 25.7 (13.8–53.4) | 0.0001 a |
| ECMO runtime (h) | 190 (114–361) | 173 (100–288) | 577 (243–1009) | 0.0001 a |
| Mechanical ventilation (d) | 11.8 (6.7–23.8) | 10.9 (6.4–19.5) | 25.4 (10.1–50.0) | 0.0001 a |
| Endpoint | ||||
| 30-day survival | 179 (52.2%) | 135 (48.0%) | 44 (71.0%) | 0.0012 b |
| ICU survival | 160 (46.6%) | 127 (45.2%) | 33 (53.2%) | 0.2636b |
| Hospital survival | 159 (46.4%) | 126 (44.8%) | 33 (53.2%) | 0.2612b |
| ECMO weaning | 197 (57.4%) | 159 (56.6%) | 38 (61.3%) | 0.5709b |
| Vent. Weaning | 169 (49.3%) | 131 (46.6%) | 38 (61.3%) | 0.0489 b |
Data given in median (interquartile range) or in number of patients (percentage of group). p-values are calculated between groups using either aMann–Whitney U-test or bFishers Exact test.
BMI, body-mass-index; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; Vent., ventilation. Bold values indicate a p-value < 0.05.
Table 2.
Patients characteristics and endpoints by best mobilization under V-V ECMO.
| Baseline characteristics | Total (n = 343) | None (n = 179) | In bed (n = 102) | Edge of bed (n = 9) | Chair (n = 33) | Standing (n = 20) | p-value |
|---|---|---|---|---|---|---|---|
| Percentage of patients | 100 | 52 | 30 | 3 | 10 | 6 | |
| Age | 55 (45–64) | 54 (44–61) | 59 (46–67) | 50 (33–66) | 56 (50–64) | 58 (36–63) | 0.2072c |
| Female gender | 108 (31.5%) | 64 (35.8%) | 26 (25.5%) | 3 (33.3%) | 11 (33.3%) | 4 (20%) | 0.3424d |
| BMI | 25.1 (23.6–30.2) | 24.5 (23.5–30.1) | 26.1 (23.9–30.6) | 28.4 (24.8–39.6) | 26.5 (23.9–31.8) | 26.0 (21.4–29.4) | 0.1174c |
| Preexisting conditions | |||||||
| Hypercholesterolemia | 41 (12%) | 20 (11.2%) | 14 (13.7%) | 2 (22.2%) | 3 (9.1%) | 2 (10%) | 0.8018d |
| Nicotine use disorder | 109 (31.8%) | 63 (35.2%) | 26 (25.5%) | 3 (33.3%) | 11 (33.3%) | 6 (30%) | 0.5746d |
| Coronary heart disease | 37 (10.8%) | 20 (11.2%) | 9 (8.8%) | 1 (11.1%) | 5 (15.2%) | 2 (10%) | 0.8937d |
| Hypertension | 124 (36.2%) | 61 (34.1%) | 37 (36.3%) | 3 (33.3%) | 16 (48.5%) | 7 (35%) | 0.6355d |
| Liver cirrhosis or chronic hepatitis | 21 (6.1%) | 18 (10.1%) | 2 (2%) | 0 (0%) | 1 (3%) | 0 (0%) | 0.0352 d |
| Chronic kidney disease | 23 (6.7%) | 11 (6.1%) | 9 (8.8%) | 1 (11.1%) | 2 (6.1%) | 0 (0%) | 0.6339d |
| Diabetes mellitus | 49 (14.3%) | 27 (15.1%) | 13 (12.7%) | 0 (0%) | 6 (18.2%) | 3 (15%) | 0.6975d |
| Oncological disorders | 59 (17.2%) | 34 (19%) | 18 (17.6%) | 0 (0%) | 4 (12.1%) | 3 (15%) | 0.5655d |
| Immunodeficiency | 93 (27.1%) | 56 (31.3%) | 27 (26.5%) | 3 (33.3%) | 4 (12.1%) | 3 (15%) | 0.1353d |
| Chronic lung disease | 97 (28.3%) | 50 (27.9%) | 29 (28.4%) | 3 (33.3%) | 9 (27.3%) | 6 (30%) | 0.9966d |
| CPR within 48 h before EMCO | 32 (9.3%) | 23 (12.8%) | 7 (6.9%) | 0 (0%) | 2 (6.1%) | 0 (0%) | 0.1494d |
| Respiratory situation before ECMO | |||||||
| Horowitz index | 70 (58–93) | 72 (60–107) | 69 (58–87) | 70 (61–102) | 63 (49–77) | 65 (46–96) | 0.0091 c |
| pO2-arterial (mmHg) | 65 (58–75) | 66 (58–78) | 64 (56–71) | 70 (59–80) | 62 (44–71) | 61 (45–73) | 0.0164 c |
| FiO2 | 1.0 (0.8–1.0) | 1 (0.8–1) | 1 (0.8–1) | 1 (0.9–1) | 1 (1–1) | 1 (0.8–1) | 0.4644c |
| pCO2-arterial (mmHg) | 56 (46–73) | 56 (46–72) | 59 (45–78) | 51 (41–115) | 54 (47–71) | 48 (40–71) | 0.6284c |
| pH–arterial | 7.3 (7.2–7.3) | 7.2 (7.2–7.3) | 7.3 (7.2–7.3) | 7.3 (7.2–7.4) | 7.4 (7.2–7.5) | 7.3 (7.3–7.4) | 0.0030 c |
| Peak inspiratory pressure ≥42 cm H2O | 33 (9.6%) | 24 (13.4%) | 6 (5.9%) | 1 (11.1%) | 0 (0%) | 2 (10%) | 0.0869d |
| ICU stay | |||||||
| Duration of ICU stay from ECMO d1 (d) | 13.7 (8.7–26.8) | 11.0 (5.9–18.0) | 17.0 (9.5–29.7) | 26.7 (14.4–57.3) | 17.8 (10.8–42.8) | 40.8 (21.7–72.6) | 0.0001 c |
| ECMO runtime (d) | 7.9 (4.7–15.0) | 147 (80–239) | 230 (147–413) | 615 (169–852) | 422 (220–778) | 782 (407–1664) | 0.0001 c |
| Mechanical ventilation (d) | 11.8 (6.7–23.8) | 9.5 (5.3–15.3) | 14.8 (8.7–26.4) | 26.7 (10.0–38.9) | 19.1 (10.5–45.2) | 38.1 (5.7–72.6) | 0.0001 c |
| Endpoints | |||||||
| 30-day survival | 179 (52.2%) | 80 (44.7%) | 55 (53.9%) | 6 (66.7%) | 22 (66.7%) | 16 (80%) | 0.0077 d |
| ICU survival | 160 (46.6%) | 78 (43.6%) | 49 (48.0%) | 4 (44.4%) | 17 (51.5%) | 12 (60%) | 0.6406d |
| Hospital survival | 159 (46.4%) | 78 (43.6%) | 48 (47.1%) | 4 (44.4%) | 17 (51.5%) | 12 (60%) | 0.6553d |
| ECMO weaning | 197 (57.4%) | 103 (57.5%) | 56 (54.9%) | 5 (55.6%) | 19 (57.6%) | 14 (70%) | 0.8136d |
| Vent. Weaning | 169 (49.3%) | 80 (44.7%) | 51 (50.0%) | 5 (55.6%) | 19 (57.6%) | 14 (70%) | 0.1981d |
Data given in median (interquartile range) or in number of patients patients (percentage of group). p-values are calculated between groups using either cKruskal–Wallis test or dChi-Square test.
BMI, body-mass-index; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; Vent., ventilation. Bold values indicate a p-value < 0.05.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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