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. 2024 Apr 18;53(6):2337–2346. doi: 10.1007/s10508-024-02861-1

Regional and Country Prevalence Estimates of Unsafe Sex Among Adolescents in 68 Low-Income and Middle-Income Countries

Janni Leung 1, Carmen Lim 1, Habte Belete 1,2,, Caitlin Mcclure-Thomas 1, Shaun Foo 1, Gary Chung Kai Chan 1
PMCID: PMC11176239  PMID: 38637452

Abstract

Prioritizing adolescent health is a public health priority to achieve the sustainable development goals, including reducing the risk of unsafe sex. Data on unsafe sex have remained scarce among adolescents in low-and middle-income countries (LMICs). To estimate the prevalence of unsafe sex in LMICs, we conducted secondary data analysis on the Global School-based Student Health Surveys among 244,863 students aged 13–17 years from 68 countries across five World Health Organization regions. The overall prevalence of ever had sex was 16.2%. The highest to lowest regional prevalence estimation of ever had sex was 30.5% (28.9–32.1) in the Americas, 28.6% (26.8–30.4) in Africa, 10.9% (9.2–12.6) in the Eastern Mediterranean, 9.6% (8.8–10.5) in South-East Asia, and 8.0% (6.8–9.1) in the Western Pacific. The highest prevalence of sexual intercourse before age 14 and practicing sexual intercourse without condom use were 36.5% (34.5–38.5) and 32.2% (30.1–34.3) in Africa, respectively. Findings suggest that current interventions are inadequate in promoting the uptake of safe sexual behaviors and an urgent intervention is needed.

Supplementary Information

The online version contains supplementary material available at 10.1007/s10508-024-02861-1.

Keywords: Adolescents, Unsafe sex, Prevalence, Global health, Low-income countries, Sexual intercourse

Introduction

Unsafe sex is a global health concern, and wherein one million deaths annually can be attributed to unsafe sex (Murray et al., 2020). Unsafe sex refers to high-risk sexual behaviors, including practicing sex at an early age, having multiple sexual partners, unprotected sex through no condom use and no birth control/contraceptives (Alimoradi et al., 2017; Nkata et al., 2019; Shayo & Kalomo, 2019). Unsafe sex is the fifth leading behavioral risk factor for all causes of disease burden in 2019, with over 46 million disability-adjusted life years attributable to it (Murray et al., 2020).

Data on unsafe sex remain limited in low- and middle-income countries (LMICs) where vulnerable populations (e.g., adolescents) may be disproportionately affected (Global Burden of Disease (GBD), 2019). Adolescence is the life period in which individuals are at increased vulnerability to external and peer influences and begin to engage in risk-taking behaviors (Madise et al., 2007). To protect the health of adolescents, the United Nations has made it a public health priority to eradicate disparities in sexual and reproductive health by 2030, as stipulated by the sustainable development goal (SDG 3)–where adolescents must have the right to comprehensive sexuality education, and universal access to contraceptive information and services (World Health Organization, 2023a).

Substantial variations in prevalence of unsafe sex are observed between high- and low-income countries. For example, in the USA, 3.9% reported having sex before age 13 (Centers for Disease Control and Prevention, 2022). In comparison, in Mozambique, 41.5% reported having early sex initiation (Pengpid & Peltzer, 2021). Such disparities may be attributed to factors that increase the risk of unsafe sexual behaviors in LMICs, such as cultural factors in low-income countries or social influences such as influenced by peer pressure, sexual experimentation, myths about contraception, poor parental supervision, poverty leading to unsafe sex, fear of partner rejection, and access barriers to reproductive health education (Govender et al., 2020).

Understanding the epidemiology of unsafe sex in LMICs is a global concern because more than half of the unintended pregnancies (World Health Organization, 2022b) and HIV human immunodeficiency virus (HIV) prevalence in adolescents are from low-middle-income countries. Unsafe sex is also associated with a range of negative health outcomes, including increased risk of transmitting HIV and other sexually transmitted infections (STI) (Kazdouh et al., 2019), unintended pregnancies, abortions (Mahumud et al., 2022), and psychological issues including suicidality (Chernick et al., 2020).

Limited data exist on unsafe sex prevalence in Low- and Middle-Income Countries (LMICs). In 43 LMICs, 52.0% of adolescents (12–15 years) had two or more sexual partners, and 44.2% did not use condoms (Smith et al., 2022). Similarly, in four Caribbean countries (2016–2017), 58.8% had multiple sexual partners, 58.6% engaged in early sexual intercourse, 41.9% lacked birth control, and 28.4% did not use condoms (Pengpid & Peltzer, 2020). Despite these findings, a comprehensive understanding of unsafe sex, incorporating more countries, diverse survey years, and a broader age range, remains underexplored. Given this, there is a need to elucidate the country-specific prevalence of unsafe sexual behaviors among adolescents residing in LMICs.

Previous studies have largely been restricted to a single or a few countries. For example, in a study of four Southeast Asian countries (Pengpid & Peltzer, 2020), the prevalence of having multiple sex partners was found to vary widely between countries, ranging from 16.1% in Laos to 73.9% in Indonesia. This further highlights the need to assess a larger pool of country-specific estimates using the same sampling approach and survey instrument such as the Global School-based Student Health Survey (GSHS).

Therefore, the current study aimed to assess the prevalence of unsafe sexual behaviors in adolescents aged 13–17 years in 68 countries across five World Health Organization (WHO) regions using the GSHS data (World Health Organization, 2023b).

Method

Participants

We used data from the GSHS implemented in 68 countries. GSHS are national school-based cross-sectional surveys among students aged 13–17 years (Centers for Disease Control and Prevention, 2018).The purpose of the GSHS surveys is to gather data on adolescent health behaviors and protective factors to support school and youth programs and policies globally. Questionnaires contain modules on alcohol, dietary behavior, drug use, mental health, hygiene, physical activity, protective factors, and tobacco use. All surveys used the same selection process, survey methodology, and standardized questionnaire (Centers for Disease Control Prevention, 2013). We included 244 863 adolescents from 68 countries. Sample sizes range from 140 in Tokelau to 28,368 in Argentina.

Procedure

Data used in the paper come from GSHS which is a complex survey which employs a two-stage, cluster sampling design to select representative sample of middle-school students in each country. In the first stage of sampling, schools are chosen based on probability proportional to enrolment size. In the second stage, specific classes are randomly selected. All students in these classes are eligible to participate. As the aim of the current analysis focuses on groups of young adolescents aged 13–17 years, this report aligns the survey procedure including the publicly available question responses, the cross-country comparability by considering the national representativeness of each survey, as well as the probability of school and classroom selection. Finally, a self-administered questionnaire was given to all students in the selected classroom. Parental consent and student assent are obtained. The ethics application was approved by the WHO. Additional details on the survey can be found here (Centers for Disease Control Prevention, 2013): https://www.cdc.gov/gshs/index.htm

Participants were from the five WHO regions: Africa region, Americas, Eastern Mediterranean Region, Western Pacific region, and South-East Asia (World Health Organization, 2023b). A total of 73 countries and territories administered the sexual risk module but only data from 68 countries could be used.

Of the total 68 countries, 16 (23.53%) were from Africa region, 28 (41.18%) Americas, 3 (4.41%) Eastern Mediterranean region, 15 (22.06%) Western Pacific region, and 6 (8.82%) South-East Asia.

Surveys lacking the outcome variable and exhibiting inconsistencies were excluded. As a result, the following surveys were excluded from our analysis because no data were available or not national representative (Colombia, Ecuador, United Arab Emirates, Venezuela, Zimbabwe). Response rates for each country range between 57% in Vanuatu to 97% in Swaziland (Eswatini).

Measures

The outcome variable, unsafe sex, was assessed through respondents’ self-disclosed engagement in risky sexual practices. These practices encompassed a lifetime history of sexual activity, initiation of sexual activity before reaching 14 years of age, involvement with multiple sexual partners, engaging in sexual activity without the use of condoms, and absence of birth control measures.

In each survey, the five binary outcome variables were coded as follows: (1) ever had sexual intercourse (coded 1 = yes, 0 = no), (2) early sexual initiation before age 14 (coded 1 = 14 years or younger, 0 = 15 + years), (3) having multiple sex partners (coded 0 = 1 or never had sex, 1 = 2 or more), (4) no condom use (coded 1 = no condom use, 0 = yes or never had sexual intercourse), and (5) no birth control (coded 1 = no birth control, 0 = yes or never had sexual intercourse).

Statistical Analysis

Prevalence of the unsafe sex variables was estimated overall, in each region, and in each country. We used the SURVEY procedure in SAS version 9.4 to account for complex sampling design in GSHS study (e.g., survey clustering, strata and primary sampling unit). The prevalence estimates were multiplied by the population sizes of the countries (age 13–17) to calculate the number of adolescents affected. Bubble plots were generated to visualize the unsafe sex variables against the prevalence of adolescents who had ever had size, with the size of the dots proportional to the number of cases of adolescents with each of the unsafe sex risk factors.

Results

Prevalence of Adolescents Who Ever Had Sex

Overall, out of 244,863 participants, 58,666 (16.2%) participants reported ever having sexual intercourse (Table 1). The prevalence of ever-had sex varied by region (Table 1). In Africa, Mozambique reported the highest ever having sexual intercourse rate at 50.7% (43.5–57.9), while the United Republic of Tanzania had the lowest at 19.0% (16.7–21.2). In the Eastern Mediterranean Region, Djibouti reported the highest ever having sexual intercourse rate at 34.7% (31.7–37.8), while Tajikistan had the lowest at 8.7% (6.9–10.6).

Table 1.

Sample characteristics and prevalence of students who had ever had sex in the Global School-based Student Health Surveys (n = 244,863)

Country Survey year Response rates Sample size Ever had sexual intercourse % (95% CI)
All Age 12–15 Age 16+
Africa
Benin 2016 78 2536 49.9 (45.7–54.1) 23.5 (18.3–28.7) 58.6 (54.7–62.5)
Botswana 2005 95 2197 19.2 (16.9–21.6) 14.7 (12.5–17) 27.4 (23–31.9)
Ghana 2012 77 3632 31.7 (27.2–36.3) 24.6 (18.9–30.3) 37.7 (32.8–42.6)
Kenya 2003 84 3691 27.0 (24.4–29.7) 24.6 (22.3–26.9) 39.2 (34.1–44.4)
Malawi 2009 94 2359 22.9 (18.2–27.6) 22.8 (18.1–27.5) 49.6 (20.8–78.4)
Mauritania 2010 70 2063 29.7 (25.1–34.3) 26.9 (21.3–32.6) 33.8 (28.8–38.7)
Mauritius 2017 84 3012 19.7 (16.3–23) 14.9 (12.4–17.5) 27.5 (21.4–33.7)
Namibia 2013 89 4531 47.1 (43.8–50.5) 31.9 (28.7–35.2) 57.8 (54.3–61.4)
Senegal 2005 60 3154 22.0 (17.3–26.6) 19.2 (15.3–23) 43 (37.7–48.3)
Seychelles 2015 82 2540 37.9 (34.4–41.4) 34 (30.4–37.7) 55.2 (48.6–61.8)
Swaziland 2013 97 3680 26.0 (23.6–28.4) 13.4 (11.5–15.4) 33.6 (30.4–36.8)
Uganda 2003 69 3215 20.4 (17.5–23.2) 15.4 (12.9–18.0) 28.4 (24.4–32.3)
United Republic of Tanzania 2014 87 3793 19.0 (16.7–21.2) 17.7 (15.1–20.2) 24.2 (20.8–27.5)
Zambia 2004 70 2257 22.4 (19.9–24.9) 19.9 (16.7–23.2) 26.6 (22.5–30.6)
Liberia 2017 71 2744 49.8 (46.4–53.2) 30.7 (26–35.3) 56.1 (52.6–59.5)
Mozambique 2015 80 1918 50.7 (43.5–57.9) 38.2 (30.3–46) 63.9 (58.6–69.1)
Africa total 47,322 28.6 (26.8–30.4) 21.8 (20.2–23.4) 42 (39.4–44.6)
Region of Americas
Anguilla 2016 88 813 32.2 (26.9–37.5) 27.6 (21.8–33.3) 44.2 (36.5–51.9)
Antigua and Barbuda 2009 67 1266 33.9 (29.4–38.5) 33.9 (29.3–38.4) 37.6 (12.4–62.9)
Argentina 2012 71 28,368 40.0 (37.2–42.9) 34.6 (31.4–37.8) 62.3 (59.4–65.2)
Barbados 2011 73 1629 33.3 (29.6–37) 32 (28.2–35.7) 49.2 (37–61.4)
Belize 2011 88 2112 23.5 (19.9–27.2) 19.1 (16.2–21.9) 44.1 (36.6–51.6)
Bolivia 2012 88 3696 24.9 (21.5–28.2) 19.6 (17.6–21.7) 41.4 (35.2–47.6)
British Virgin Islands 2009 90 1664 37.8 (37.8–37.8) 30.5 (30.5–30.5) 58.6 (58.6–58.6)
Cayman Islands 2007 79 1299 37 (37–37) 35.9 (35.9–35.9) 44.7 (44.7–44.7)
Chile 2013 60 2049 37.9 (32.6–43.2) 23.5 (20.1–26.9) 56.8 (48.7–65)
Costa Rica 2009 72 2679 23.5 (19.3–27.7) 18 (15.8–20.1) 51.4 (42.1–60.7)
Dominica 2009 84 1642 45 (40.3–49.6) 39.4 (35.3–43.5) 67.4 (60.8–74)
Grenada 2008 78 1542 42.6 (37.6–47.6) 36 (32.9–39) 73.3 (65–81.5)
Guatemala 2015 82 4374 19.5 (16.2–22.8) 15.4 (12.9–17.9) 38.6 (29.3–47.9)
Guyana 2010 76 2392 31.8 (27–36.7) 29.3 (25.1–33.5) 45.8 (36.4–55.3)
Honduras 2012 79 1779 24.7 (22.2–27.3) 21.4 (18.8–24) 45.6 (40–51.3)
Jamaica 2017 60 1667 46.8 (40.6–53) 36.9 (30.8–43) 58.1 (51.3–64.9)
Peru 2010 85 2882 19.4 (16.7–22) 16.8 (14.6–19) 32.1 (25.5–38.6)
Saint Kitts and Nevis 2011 70 1740 36.1 (36.1–36.1) 30.8 (30.8–30.8) 59.6 (59.6–59.6)
Saint Lucia 2007 77 1276 34.2 (29.8–38.5) 30.6 (26.2–34.9) 53.5 (45–62.1)
Saint Vincent and the Grenadines 2007 84 1333 39.9 (33.7–46.1) 37.8 (31.2–44.4) 61.7 (52.8–70.6)
Suriname 2016 83 2126 32.3 (23.4–41.2) 19 (14.1–23.9) 60.6 (52–69.1)
Trinidad and Tobago 2017 89 3869 26.2 (22.4–30) 21.7 (18.5–25) 39.1 (31–47.3)
Uruguay 2012 77 3524 33.7 (30.6–36.9) 27.5 (24.9–30.1) 64.2 (58.9–69.6)
Bahamas 2013 78 1357 28.2 (24–32.4) 26.4 (22.8–30.1) 71.8 (47.3–96.3)
El Salvador 2013 88 1915 22.4 (19.2–25.7) 18.6 (16–21.1) 45.8 (36.7–54.9)
Curacao 2015 83 2765 36.9 (32.3–41.5) 18.7 (16–21.3) 55.7 (51.1–60.2)
Paraguay 2017 87 3149 28.6 (24.4–32.8) 16.8 (14.3–19.3) 47.4 (42.5–52.2)
Dominican Republic 2016 63 1481 40.7 (32.8–48.5) 32.4 (26.2–38.7) 48.3 (37.5–59.1)
Americas total 86,388 30.5 (28.9–32.1) 23.2 (22.1–24.3) 50.6 (47.4–53.8)
Eastern Mediterranean region
Tajikistan 2006 80 9714 8.7 (6.9–10.6) 9.2 (7–11.3) 7.1 (5–9.2)
Macedonia 2007 2114 15.9 (11.8–19.9) 12.4 (9.4–15.4) 29 (21.3–36.6)
Djibouti 2007 83 1777 34.7 (31.7–37.8) 29.7 (25.6–33.8) 39.4 (36.2–42.7)
Eastern Mediterranean total 13,605 10.9 (9.2–12.6) 10.2 (8.5–12) 12.8 (10.1–15.5)
South-East Asian region
Indonesia 2015 94 11,142 5.8 (4.7–6.9) 6 (4.7–7.2) 4.6 (3.4–5.9)
Thailand 2015 89 5894 19.1 (17.2–20.9) 14.8 (12.3–17.4) 28.4 (23.5–33.3)
Bangladesh 2014 91 2989 8.2 (6–10.3) 8.6 (6.4–10.9) 3.1 (0.2–6)
Bhutan 2015 79 7576 17.1 (15.5–18.7) 11.7 (10.4–13.1) 21.5 (19.5–23.5)
Timor Leste 2016 95 3704 22.1 (19.5–24.8) 18.1 (14.4–21.8) 24.8 (21.8–27.8)
Nepal 2015 69 6529 19.2 (16–22.5) 18 (14.6–21.4) 22.1 (18.2–26.1)
South-East Asia total 37,834 9.6 (8.8–10.5) 8.8 (7.8–9.8) 12.9 (10.1–15.6)
Western Pacific Region
Cambodia 2013 85 3806 11.6 (10.1–13.2) 12.6 (10.5–14.7) 10.6 (8.7–12.5)
Fiji 2016 79 3705 21.3 (16.1–26.6) 16.8 (12–21.5) 25.1 (18.5–31.7)
Kiribati 2011 85 1582 23.5 (20.7–26.4) 21.2 (18.8–23.7) 36.4 (28.8–44)
Malaysia 2012 89 25,507 8.2 (7.4–8.9) 7.9 (7–8.9) 8.5 (7.5–9.5)
Mongolia 2013 88 5393 15.1 (12.8–17.5) 9.6 (8.2–10.9) 26.3 (22–30.7)
Nauru 2011 73 578 31.7 (31.7–31.7) 28.1 (28.1–28.1) 43.4 (43.4–43.4)
Samoa 2017 59 1955 25 (21.4–28.7) 21.3 (17.4–25.2) 29.7 (25–34.3)
Vanuatu 2016 57 2159 26.8 (23.5–30.2) 21.4 (18.3–24.5) 33.8 (28–39.5)
Vietnam 2013 96 3331 6.7 (5–8.4) 3.9 (3–4.9) 8.8 (6.1–11.6)
Brunei 2014 65 2599 11.4 (9.9–12.8) 10 (8.3–11.6) 14.8 (11.6–18)
Tuvalu 2013 90 943 18.6 (18.6–18.6) 16.1 (16.1–16.1) 24.1 (24.1–24.1)
French Polynesia 2015 70 3216 40.1 (34.1–46.1) 28.4 (24.8–32) 61.8 (56.9–66.6)
Laos 2015 70 3683 14.5 (12.2–16.8) 9.2 (7.3–11.1) 17.9 (15–20.8)
Tokelau 2014 71 140 30.2 (21.9–38.5) 19.4 (13.4–25.4) 63.1 (49.9–76.2)
Wallis and Futuna 2015 82 1117 26.8 (23.3–30.3) 20.8 (16.8–24.8) 36.8 (32–41.6)
Western Pacific total 59,714 8.0 (6.8–9.1) 6.1 (5.3–7) 9.7 (7.7–11.7)
Total 244,863 16.2 (15.4–17) 13.1 (12.3–13.9) 23.2 (21.1–25.3)

In South-East Asia, Timor Leste reported the highest ever having sexual intercourse rate at 22.1% (19.5–24.8), while Indonesia had the lowest at 5.8% (4.7–6.9). In the Western Pacific region, French Polynesia reported the highest ever having sexual intercourse rate at 40.1% (34.1–46.1), while Vietnam had the lowest at 6.7% (5.8–4.0).

Among adolescents aged 16 and older, the Americas had the highest prevalence at 50.6% (47.4–53.8), followed by Africa at 42.0% (39.4–44.6). The Western Pacific region had the lowest prevalence at 9.7% (7.7–11.7), followed by the Eastern Mediterranean Region at 12.8% (10.1–15.5), and South-East Asia at 12.9% (10.1–15.6).

For adolescents aged 12–15, the Americas had the highest prevalence at 23.2% (22.1–24.3), followed by Africa at 21.8% (20.2–23.4). The Western Pacific region had the lowest prevalence at 6.1% (5.3–7.0), followed by South-East Asia at 8.8% (7.8–9.8), and the Eastern Mediterranean Region at 10.2% (8.5–12.0) (Table 1).

Prevalence of Unsafe Sex

The overall prevalence of sexual intercourse before age 14 was 31.4% (30–32.9). The prevalence of having multiple sex partners was 33.2% (31.8–34.6). Prevalence of no condom use was 27.4% (25.9–28.8) and 21.2% (20.1–22.4) was no birth control used (Table 2).

Table 2.

Regional- and country-level prevalence of unsafe sex and high-risk sexual behaviors

Prevalence of unsafe and high-risk sex among those who ever had sex % (95%CI)
Sexual intercourse before age 14 Multiple sex partners No condom use during sexual intercourse No birth control methods during sexual intercourse
Total 31.4 (30–32.9) 33.2 (31.8–34.6) 27.4 (25.9–28.8) 21.2 (20.1–22.4)
Regional-level estimates
Africa 36.5 (34.5–38.5) 34.5 (32.5–36.5) 32.2 (30.1–34.3) 19.2 (17.5–20.9)
Region of Americas 35.2 (33–37.3) 46.7 (44.6–48.8) 28.3 (26.5–30) 32.7 (31–34.4)
Eastern Mediterranean Region 36.3 (31.2–41.4) 30.6 (26.6–34.6) 18.6 (15–22.2)
South-East Asian Region 26.8 (23.4–30.2) 31.7 (18.9–24.4) 20.9 (17.5–24.3) 15.3 (13.3–17.3)
Western Pacific Region 14.9 (11.9–17.9) 21.8 (18–25.7) 24.3 (19.3–29.3) 14.6 (11.2–17.9)
Country-level estimates
 Africa
  Benin 23.4 (18.9–28) 61.2 (57.3–65.1) 47.3 (41.8–52.8) 41.2 (37.9–44.5)
  Botswana 43.7 (37.8–49.7) 45.6 (39.4–51.9) 27.5 (23.3–31.6)
  Ghana 25.6 (21.9–29.4) 33.8 (30–37.5) 33.2 (28.1–38.3) 27.8 (23.6–32.1)
  Kenya 68.9 (64–73.9) - 49.2 (45.4–53.1)
  Malawi 40.2 (33.2–47.2) 22.5 (14.2–30.9) 13.8 (9.2–18.4)
  Mauritania 33.8 (28.7–38.8) 33.9 (27.4–40.5) 21.5 (16–27) 18.5 (13.5–23.5)
  Mauritius 27 (22.1–31.8) 38.9 (32.7–45) 35.2 (29.1–41.4) 39 (34.9–43)
  Namibia 32.9 (29.4–36.3) 49.3 (46–52.5) 19.5 (16.9–22.1) 30.7 (27.5–34)
  Senegal 65.3 (55.9–74.8) 58.2 (52.6–63.8) 37.5 (27.3–47.7)
  Seychelles 51.4 (47.1–55.8) 53.7 (49.5–57.9) 38.8 (34.8–42.8) 48.7 (44.1–53.2)
  Swaziland 44.8 (41.4–48.3) 25 (22–28.1) 36.9 (33.9–39.9)
  Uganda 46.3 (40.8–51.7) 48.1 (44.1–52.1) 32.4 (26.8–38)
  United Republic of Tanzania 37.2 (31.7–42.6) 26.9 (23–30.8) 29.3 (24.5–34.1) 17.6 (14.1–21.1)
  Zambia 53.2 (46.5–59.9) 47.4 (43.6–51.2) 34.6 (28.6–40.5)
  Liberia 15.1 (12.3–18) 45.1 (41.6–48.6) 27.5 (24.8–30.3) 20.5 (17.4–23.6)
  Mozambique 28.4 (24.7–32.2) 40.8 (35–46.7) 17.5 (14.2–20.8) 23.4 (18.7–28.1)
 Region of Americas
  Anguilla 44.4 (35.9–52.9) 47.8 (41.3–54.2) 28.4 (23.3–33.5) 39.4 (33.8–44.9)
  Antigua and Barbuda 67.3 (62–72.6) 62.6 (58.2–67) 27.7 (23.1–32.3) 51.3 (46.8–55.9)
  Argentina 41.6 (39–44.2) 48.5 (45.9–51) 19.6 (17.4–21.8) 30.8 (27.9–33.8)
  Barbados 51.3 (46.1–56.4) 48.3 (43.2–53.3) 29 (25.4–32.6) 45.8 (41.5–50)
  Belize 45.3 (40.4–50.2) 52.7 (47.7–57.7) 24.3 (20–28.6) 37.1 (31.9–42.2)
  Bolivia 30.5 (25.7–35.3) 39.4 (35.3–43.4) 29.4 (25.7–33.1) 29.2 (26–32.3)
  British Virgin Islands 58 (58–58) 58.4 (58.4–58.4) 23.9 (23.9–23.9) 35.2 (35.2–35.2)
  Cayman Islands 64.7 (64.7–64.7) 52.8 (52.8–52.8) 24 (24–24)
  Chile 23.4 (17.6–29.1) 44.5 (36.9–52.1) 39 (33.6–44.4) 33.5 (27.9–39.1)
  Costa Rica 36.8 (32.6–41) 44.7 (35.7–53.7) 32 (25.3–38.7) 25 (21.4–28.5)
  Dominica 60.9 (56.1–65.7) 59 (54.7–63.2) 29.7 (25.9–33.4) 52.8 (48.1–57.5)
  Grenada 61.7 (57.8–65.6) 55.2 (50.5–59.9) 30.4 (26.5–34.2)
  Guatemala 31.5 (24.6–38.5) 41.9 (32.5–51.3) 29.6 (22.7–36.4) 31.8 (25.6–38.1)
  Guyana 47.6 (43.4–51.8) 46.8 (44–49.6) 23.4 (20.6–26.3)
  Honduras 39.5 (33.8–45.2) 34.7 (31–38.4) 23.5 (19.7–27.2) 26.8 (22.4–31.2)
  Jamaica 53.7 (48.1–59.3) 63.6 (59.7–67.5) 30.4 (26–34.8) 44 (39–48.9)
  Peru 41.8 (37.6–46.1) 46.9 (43.1–50.6) 32.6 (28.9–36.2) 41.3 (36.9–45.8)
  Saint Kitts and Nevis 52.5 (52.5–52.5) 58.5 (58.5–58.5) 37.1 (37.1–37.1) 46.4 (46.4–46.4)
  Saint Lucia 60 (52.8–67.1) 55.5 (50.7–60.3) 37.4 (31.9–42.8)
  Saint Vincent and the Grenadines 68.8 (63.7–73.8) 55.2 (49.8–60.6) 30.8 (26.1–35.5)
  Suriname 33.1 (26.5–39.8) 50.3 (43.8–56.7) 30 (24.7–35.2) 40.4 (36.9–43.8)
  Trinidad and Tobago 37.3 (32.8–41.8) 43.1 (37.6–48.6) 31.1 (27.6–34.7) 38.7 (35.6–41.7)
  Uruguay 30.4 (26.4–34.5) 45.7 (43.5–47.9) 15.6 (13.2–18.1) 34.1 (31.4–36.8)
  Bahamas 62.7 (57.2–68.2) 42.2 (37.5–47) 26.2 (19.9–32.4) 38.1 (31.7–44.4)
  El Salvador 39.8 (36.2–43.4) 41.5 (36.1–46.9) 21.7 (17.1–26.3) 34.1 (28.4–39.7)
  Curacao 23.9 (20.5–27.4) 50.5 (47.4–53.5) 38.2 (34.2–42.3) 39.5 (36.6–42.3)
  Paraguay 19 (15.7–22.2) 48.9 (45.7–52.1) 24.1 (20.9–27.3) 34.3 (30.2–38.4)
  Dominican Republic 40.8 (34.8–46.8) 54.9 (47.9–61.8) 25.3 (21.7–28.9) 28.9 (24.3–33.5)
 Eastern Mediterranean region
  Tajikistan 35.5 (28.6–42.3) 22.1 (17.1–27.1) 17.2 (11.9–22.6)
  Macedonia 39.1 (29.4–48.8) 41.1 (35.6–46.5) 17.8 (13.3–22.3)
  Djibouti 32.6 (27.8–37.5) 55 (50.6–59.4) 30.7 (25.6–35.7)
 South-East Asian Region
  Indonesia 21.5 (16.6–26.4) 21.2 (17.5–24.9) 19.3 (16–22.5) 15.3 (12.6–18)
  Thailand 28.6 (24–33.1) 37.5 (33.3–41.7) 21.2 (16.7–25.8) 17.7 (14.8–20.6)
  Bangladesh 37.1 (23.6–50.5) - 30.6 (16.6–44.5) 14.8 (7.2–22.4)
  Bhutan 28.4 (24.6–32.1) 42.3 (39.3–45.4) 25.8 (22.4–29.3) 30.1 (26.7–33.4)
  Timor Leste 22.5 (18.1–26.9) 30.6 (25.7–35.6) 25.8 (21.9–29.7) 19.8 (16.1–23.5)
  Nepal 23 (17.9–28.1) 18.7 (13.5–23.9) 13.3 (9.5–17.2) 11.5 (8.2–14.8)
 Western Pacific Region
  Cambodia 8.6 (5.3–12) 8.8 (4.8–12.7) 6.1 (4.4–7.8) 7.5 (5.5–9.4)
  Fiji 29.3 (24.9–33.7) 39.9 (35–44.8) 29.8 (24.4–35.3) 29.7 (24.6–34.7)
  Kiribati 34 (29.6–38.4) 39.2 (34.5–43.9) 51.5 (45–58) 31.1 (26–36.1)
  Malaysia 15.8 (13.3–18.3) 16.9 (14.2–19.7) 19.3 (16.3–22.3) 10.6 (8.8–12.3)
  Mongolia 19.1 (16–22.1) 35.8 (31.4–40.1) 29.4 (25.4–33.5) 31.6 (26.4–36.9)
  Nauru 36.5 (36.5–36.5) 48.2 (48.2–48.2) 30.3 (30.3–30.3)
  Samoa 23 (17.8–28.2) 32 (25.2–38.8) 26.2 (20.5–31.9) 25.2 (20.6–29.7)
  Vanuatu 15.9 (12.3–19.5) 31.8 (26.7–36.9) 26.9 (21.8–32.1) 19.8 (15.7–24)
  Vietnam 15.2 (10–20.4) 23.4 (16.9–29.8) 28.8 (20.7–36.9) 15.5 (9.8–21.2)
  Brunei 17.4 (12.8–22) 17.9 (11.6–24.1) 18.9 (13–24.7) 16.2 (11.7–20.8)
  Tuvalu 29.8 (29.8–29.8) 34.5 (34.5–34.5) 28.7 (28.7–28.7) 20.9 (20.9–20.9)
  French Polynesia 29.3 (24.7–34) 47.3 (42.9–51.7) 45.8 (41.3–50.3) 38.8 (36.2–41.4)
  Laos 8.3 (4.4–12.1) 28.8 (21.9–35.6) 21 (15.6–26.3) 10 (7.8–12.2)
  Tokelau 43.3 (30.8–55.8) 53.7 (43.2–64.2) 60.2 (44.3–76.1) 50 (46.1–53.9)
  Wallis and Futuna 36.4 (28.4–44.5) 51.2 (44.4–58) 39.1 (32.6–45.6) 37.7 (30.7–44.8)

In Africa, the highest proportion of sexual intercourse before age 14 (36.5%) and practicing sexual intercourse without condom use (32.2%) were reported. In the Americas, the highest rates of multiple sexual partners (46.7%) and sexual intercourse without birth control methods (32.7%) were reported. In the Western Pacific region, the lowest proportion of sexual intercourse before age 14 (14.9%) and practicing sexual intercourse without birth control methods (14.6%) were reported.

There were country-level differences within the regions. In Africa, Kenya reported the highest rate of sexual intercourse before age 14 at 68.9%, followed by Senegal at 65.3% and Zambia at 53.2%. Benin reported the highest rates of multiple sexual partners (61.2%), while Seychelles and Kenya reported the highest proportions of intercourse without birth control (48.7%) and without condom use (49.2%), respectively. Liberia reported the lowest rate of sexual intercourse before age 14 (15.1%), while Malawi had the lowest rates of multiple sexual partners (22.5%), and intercourse without condom use (13.8%).

In the Americas, Saint Vincent and the Grenadines reported the highest rates of sexual intercourse before age 14 (68.8%). Jamaica, Chile, and Dominica reported the highest rates of multiple sexual partners (63.6%), intercourse without condom use (39.0%), and without birth control methods (52.8%), respectively. Paraguay reported the lowest rates of sexual intercourse before age 14 (19.0%). Honduras, Uruguay, and Costa Rica reported the lowest rates of multiple sexual partners (34.7%), intercourse without condom use (15.6%), and without birth control methods (25.0%), respectively.

In the Eastern Mediterranean Region, Macedonia reported the highest rates of sexual intercourse before age 14 (39.1%). Djibouti had the highest proportions of having multiple sexual partners (55.0%) and intercourse without condom use (30.7%). Djibouti reported the lowest rates of sexual intercourse before age 14 (32.6%). Tajikistan had the lowest rates of multiple sexual partners (22.1%) and intercourse without condom use (17.2%). No data on birth control methods were available.

In the South-East Asian Region, Bangladesh reported the highest rates of sexual intercourse before age 14 (37.1%) and intercourse without condom use (30.6%). Bhutan reported the highest rates of multiple sexual partners (42.3%) and intercourse without birth control methods (30.1%). Nepal recorded the lowest rates of multiple sexual partners (18.7%), intercourse without condom use (13.3%), and no birth control methods (11.5%). Indonesia reported the lowest rates of sexual intercourse before age 14 (21.5%).

In the Western Pacific Region, Tokelau recorded the highest rates for sexual intercourse before age 14 (43.3%), multiple sexual partners (53.7%), intercourse without condom use (60.2%), and no birth control methods (50.0%). Laos recorded the lowest rates of sexual intercourse before age 14 (8.3%). Cambodia reported the lowest rates of multiple sexual partners (8.8%), intercourse without condom use (6.1%), and no birth control methods (7.5%).

The estimated prevalence of unsafe sex factors against the prevalence of ever having sex with sizes representing the corresponding number of adolescents of the countries at risk is presented in Supplement 1 (data table) and Supplement 2 Figs. 16. In Africa, the prevalence of ever-had sex was high in Mozambique, Benin, and Liberia. Benin had both a high prevalence of ever-had sex and unsafe sex. Senegal had a low prevalence of ever had sex although had high unsafe sex. In the Americas, the prevalence of ever-had sex was high in Jamaica, Dominica, and Grenada. Jamaica and Dominica had both high ever had sex and unsafe sex. Peru had low ever-had sex but high unsafe sex. In the Eastern Mediterranean, the prevalence of ever-had sex was high in Djibouti. Djibouti had both high ever had sex and unsafe sex. In Southeast Asia, the prevalence of ever-had sex was high in Timor Leste, Nepal, and Thailand. Timor Leste and Thailand both reported high ever-had sex and unsafe sex. Bangladesh had both low ever had sex but high unsafe sex. In the Western Pacific, the prevalence of ever-had sex was high in French Polynesia, Nauru, and Tokelau. Tokelau had both high ever had sex and unsafe sex. Although the prevalence was relatively low, Indonesia has the highest total number of adolescents who had unsafe sex due to its large population size (multiple sex partners = 21.2%, 9.7 million cases, no condom use = 19.3%, 8.8 million cases, sex before age 14 = 21.5%, 9.8 million cases, no birth control = 15.3%, 7.0 million cases).

Discussion

We analyzed data from 68 countries using the GSHS and found a significant prevalence of unsafe sexual practices. The rates for unsafe sexual practice (multiple sexual partners, early sexual intercourse, having sex without a condom, and no birth control during intercourse) varied across regions. Our results are notably lower than those from a study involving 43 low- and middle-income countries (e.g., 52.0% with multiple partners, 44.2% without condom use) (Smith et al., 2022) and four Caribbean countries study (Pengpid & Peltzer, 2020) using the same GSHS data. The variation in prevalence is primarily due to differences in participant age ranges, year of the survey, and number of included countries. The previous study in low- and middle-income countries focused on ages 12–15, while the Caribbean countries survey only covered the years 2016 and 2017. Unlike the previous study, our research covers a broader scope with more countries, varied survey years, and a wider age range of participants.

The early initiation of sexual practice was common in the Americas and Africa. However, the prevalence of unsafe sex was notably higher in Africa, which may be attributed to a combination of cultural influences and risky school environments (Ngidi & Essack, 2022). Such behavior could affect students’ physical and psychological health (Mahumud et al., 2022; Odimegwu et al., 2019; Seff et al., 2021), underscoring the importance of developing targeted interventions aimed at improving the wellbeing of adolescents in these regions and the need to commit to the SDGs, including universal health coverage (SDG Target 3.8) (World Health Organization, 2022c).

The African Region also had a higher proportion of sexual practices without condom use. The sub-Saharan African countries are home to more than two-thirds of people in the world living with HIV. Condom use is known to be one of the most critical components of HIV prevention. The majority religion in Sub-Saharan African countries is Christianity, in which there is a moral objection to condom use and other contraceptive use in some south African countries (Muula, 2010). This cultural influence could be one of the major reasons why the African Region had the highest prevalence of sex without a condom. It has also been shown that in these countries, misinformation about condom efficacy is high (Winskell et al., 2011). The UN considers sexual education as a human right. The strategies and efforts put in place should include additional efforts on sexual and reproductive education in school settings too.

There is a substantial heterogeneity in the prevalence of sexual practice without birth control, with the highest prevalence recorded in the American region. The high prevalence in the American region could be explained by socioeconomic inequality where there are large wealth inequalities in the contraceptive use (Leon et al., 2019). Proper sex education is essential to lower the prevalence of unsafe sex in the American region as sex is seen as a taboo topic that is not often discussed. This study supports the call for action to meet the sustainable development goals SDGs, target 3.7 to “ensure universal access to sexual and reproductive health-care services, including integration of reproductive health into national strategies and programmes” by 2030 (United Nations, 2019).

This study indicates the need for future action to reduce unsafe sex among students. There are more than 21 million pregnancies each year among adolescents in low- and middle-income countries and 50% were unintended (Sully et al., 2020; World Health Organization, 2022b). Therefore, school-based (Maina et al., 2021) and family-based interventions (Downing et al., 2011) are recommended to help reduce the prevalence of unsafe sex among students and to meet the UN 2030 SDG Goals (World Health Organization, 2021). Acknowledging that progress has been made to reduce unsafe sexual practices among students, the UN SDG Goals (Cluver et al., 2019), WHO’s Global Accelerated Action for the Health of Adolescents (AA-HA!) (World Health Organization, 2017), and the UN Universal Declaration of Human Rights continues to call upon further action to improve sexual health in adolescents around the world (World Health Organization, 2022a).

The GSHS is cross-sectional, and therefore, the results cannot infer causation. The data were collected on self-reports, possibly leading to under or over-reporting of adolescents’ sexual behavior. Some surveys included in this study date back to 2003 indicating that some data would not be representative of adolescents today. There were limited countries included (n = 3) for the Mediterranean region as the data were unavailable for the remaining countries in this region. Future studies could explore country-level correlates of unsafe sex. As this study was conducted at the school level, the data were not representative of adolescent school dropouts which have been associated with greater levels of sexual risk and vulnerability, especially in girls (Anderson & Pörtner, 2014).

In conclusion, our findings revealed that the prevalence of unsafe sex behaviors was highest in the American and African regions, and some countries in Southeast Asia had a relatively low prevalence but a large number of total cases due to large population sizes. This study underscores the necessity for targeted interventions and policy measures tailored to specific regions to address and reduce the prevalence of unsafe sexual behaviors in those regions. Global efforts to prevent unsafe sex and attributable disease burden in adolescents also need to consider both prevalence rates and cases to meet the UN 2030 SDG Goals.

Supplementary Information

Below is the link to the electronic supplementary material.

Acknowledgements

We thank the summer research scholars, supported by The University of Queensland summer research scholarships, for contributions to earlier stages of this work.

Author Contributions

GC and JL conception or design. CL, JL, and GC acquisition and analysis. All authors contributed to interpretation of data for the work. JL, CL, HB, and CM were involved in drafting. JL, CM, HB, CL, and GC contributed to revising draft. All authors approve the version to be published and agree to be accountable for the work.

Funding

Open Access funding enabled and organized by CAUL and its Member Institutions. The National Centre for Youth Substance Use Research (NCYSUR) is supported by the Australian Government Department of Health under the Drug and Alcohol Program. JL, CL, and GC are supported by the Australian National Health and Medical Research Council (NHMRC). HB is supported by The University of Queensland research and training program scholarship.

Data Availability

The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.

Declarations

Conflict of interest

All authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Ethical Approval

The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the paper; and decision to submit the paper for publication.

Footnotes

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Associated Data

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Supplementary Materials

Data Availability Statement

The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.


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