Table 4. The comparison test of angiogenic factors in the placenta and maternal plasma between the case and control group.
| Variable | Controls (n=14)
Mean ± SD |
Cases (n=19)
Mean ± SD |
p-value | |||
|---|---|---|---|---|---|---|
| Placenta
(Mean fluorescence intensity) |
Plasma | Placenta
(Mean fluorescence intensity) |
Plasma | Placenta | Plasma | |
| VEGF | 226,693 ± 39,025 | 50.82 ± 2.41
(pg/mL) |
64,404 ± 28,942 | 51.04 ± 1.99
(pg/mL) |
0.00 * | 0.77 * |
| PlGF | 84,693,238 ± 29,981,727 | 116.00 ± 26.19
(ng/mL) |
22,814,440 ± 9,497,663 | 100.47 ± 10.72
(ng/mL) |
0.00 * | 0.03 * |
| VEGFR-1 | 213,410 ± 35,251 | 12.49 ± 4.57
(ng/mL) |
107,444 ± 46,695 | 9.41 ± 3.86
(ng/mL) |
0.00 * | 0.04 * |
| VEGFR-2 | 167,673,566 ± 90,824,566 | 12257 ± 5482
(pg/mL) |
96,968,870 ± 24,300,623 | 9271 ± 2419
(pg/mL) |
0.02 ** | 0.04 * |
| HIF-1α | 25,286,646.1±27,238,953 | 44.94 ± 15.49
(pg/mL) |
80,375,094 ± 40,647,360 | 43.24 ± 20.19
(pg/mL) |
0.00 ** | 0.40 ** |
Notes: *) T-test **) Mann-Whitney test SD=standard deviation.