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Receiver operating characteristic of SHOX2 methylation in plasma. ROC curve displaying the diagnostic accuracy of SHOX2 methylation levels in plasma to differentiate between lung cancer (n = 30) and benign lung disease (n = 15). The area under the curve (AUC) is 0.698, with a sensitivity of 56.67% and specificity of 86.67% at the optimal cut-off value of ≤11.855.
