Figure 9.

(a) H and E staining images of a UV-irradiated BALB/c mouse skin model treated with composite hydrogel films: (a) normal skin, (b) 311 nm UV-irradiated skin, (c) hydrogels without Pyruvate and lactic acid, (d–f) hydrogels with different lactate concentrations (12.8, 6.4, and 3.2 mM), and (g–i) hydrogels with varied pyruvate levels (200, 100, and 50 mM); reproduced with permission from ref. [114]. Copyright, Elsevier. (b) An illustration of a schematic diagram showing how the IFI6-PDA@GO/SA is fabricated and how it is used to heal RISIs (radiation-induced skin injuries) [115].