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Renal function of rats in each group (n = 3–9)
Serum creatinine (A) and BUN (C) of rats at the age of 12,18 and 21 months in each group. The trends of Serum creatinine (B) and BUN (D) levels of rats in each group with aging. Values are presented as means ± SD. ▲ p＜0.05, ▲▲ p < 0.01, ▲▲▲<0.001, ▲▲▲▲p＜0.0001 versus the control group, ∗p < 0.05, ∗∗p < 0.01 versus 1/6NX group, ##p＜0.01 versus the UNX group.
