Figure 6.

(I) (A) Development of DOX/Au@Pt-cRGD; (B) The ability of nanomedicine to reduce DOX-induced organ oxidative damage, particularly cardiomyopathy during chemotherapy, is a result of its ROS scavenging capabilities, which are achieved through the catalysis of platinum shells. (II) Using Au@Pt to direct imaging in vivo. (A) Pre- and post-intravenous injection of DOX/Au@Pt-cRGD and DOX/Au@Pt-PEG to tumor-bearing animals undergoing PA imaging in vivo. (B) In vivo photothermal processing of DOX/Au@Pt-cRGD (C) Image of heart, liver, and kidney tissue treated using various fluorescent microscopy techniques. Reproduced with the permission from ref. 96. Scheme 1, Fig. 5, and Fig. 8 (ACS Publication©2018).