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. 2002 Jan 5;324(7328):8. doi: 10.1136/bmj.324.7328.8b

Adverse reactions to drugs increase

Lynn Eaton 1
PMCID: PMC1121978  PMID: 11777789

The number of patients who die in England and Wales after errors in drug prescribing or from an adverse drug reaction is showing a marked upward trend, the Audit Commission has warned.

The commission estimated that just under 11% of patients on hospital medical wards experience an adverse event, such as being given the wrong drug or having an adverse reaction to a drug.

Such an event, although not fatal, can lead on average to an additional stay in hospital of 8.5 days, costing the NHS as much as £1.1bn ($1.5bn; €1.8bn).

“The problem is that nobody really knows the extent of the problem,” said the report's author, Nick Mapstone. Only one hospital that was visited had a comprehensive system of reporting errors.

Errors included giving patients with cancer temazepam when they should have received tamoxifen; giving a contraceptive steroid instead of an antipsychotic injection; and prescribing an anticancer medicine at 1000 times the correct dose. The commission estimated that nearly half these events were preventable.

A Spoonful of Sugar is available from Audit Commission Publications, PO Box 99, Wetherby LS23 7JA. graphic file with name 16725.jpg


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