Table 1.
Demographics and clinical characteristics of patients with viral sepsis and viral non sepsis groups with COVID-19
| All (n = 231) | VNS group (n = 186) | VS group (n = 45) | P | |
|---|---|---|---|---|
| Age/[years，Md(IQR)] | 76.00 (67.00，85.00) | 75.00 (64.00, 84.00) | 83.0 (72.00, 90.00) | ＜0.001 |
| Gender/(n，%) | ||||
| Male | 132 (57.1) | 107 (57.5) | 25 (55.6) | 0.810 |
| Female | 99 (42.9) | 79 (42.4) | 20 (44.4) | |
| Classification of COVID-19/(n，%) | ||||
| Severe condition | 79 (34.2) | 41 (22.0) | 38 (84.4) | ＜0.001 |
| Non-severe condition | 152 (65.8) | 145 (78.0) | 7 (15.6) | |
| Underlying Conditions/(n，%) | ||||
| Hypertension | 128 (55.4) | 100 (53.7) | 28 (62.2) | 0.306 |
| Type 2 diabetes | 67 (29.0) | 55 (29.6) | 12 (26.7) | 0.700 |
| Coronary heart disease | 86 (37.2) | 62 (33.3) | 24 (53.3) | 0.013 |
| Cerebrovascular disease | 46 (19.9) | 35 (18.8) | 11 (24.4) | 0.396 |
| Smoking History/(n，%) | 31 (13.4) | 27 (14.5) | 4 (8.9) | 0.320 |
| Alcohol History/(n，%) | 23 (10.0) | 23 (12.4) | 0 (0) | 0.027 |
| Time from Symptoms to Admission/[d，Md(IQR)] | 10.00 (6.00，14.00) | 10.00 (5.00, 14.00) | 10.00 (7.00, 12.00) | 0.650 |
| Length of Hospital Stay/[d，Md(IQR)] | 12.00 (7.00，16.00) | 12.00 (7.75, 16.00) | 11.00 (6.00, 20.50) | 0.965 |
| Hospitalization Cost/[10,000 RMB，Md(IQR)] | 1.54 (0.81，2.73) | 1.41 (0.81, 2.52) | 2.48 (0.83, 7.81) | ＜0.001 |
| ICU Admission/[d，Md(IQR)] | 16 (6.9) | 5 (2.7) | 11 (24.4) | ＜0.001 |
| ICU Length of Stay/[d，Md(IQR)] | 11.0 (5.25, 16.0) | 10.50 (7.75, 13.75) | 11.50 (3.75, 16.75) | ＜0.001 |
| BMI (kg·m−2， ± s) | 24.32 ± 3.44 | 24.39 ± 3.21 | 24.03 ± 4.36 | 0.654 |
| Treatment/(n，%) | ||||
| High-flow nasal oxygen | 53 (22.9) | 42 (22.6) | 11 ( (24.4) | 0.790 |
| Invasive mechanical ventilation | 15 (6.5) | 0 (0) | 15 (33.3) | ＜0.001 |
| Non-invasive mechanical ventilation | 7 (3.0) | 0 (0) | 7 (15.5) | ＜0.001 |
| Complications/(n，%) | ||||
| ARDS | 61 (26.4) | 28 (15.1) | 33 (73.3) | ＜0.001 |
| Respiratory failure | 38 (16.5) | 10 (5.4) | 28 (62.2) | ＜0.001 |
| Bacterial pneumonia | 55 (23.8) | 30 (16.1) | 25 (55.6) | ＜0.001 |
| Fungal pneumonia | 11 (4.8) | 4 (2.2) | 7 (15.6) | ＜0.001 |
| Cardiac injury | 28 ( (12.1) | 9 (4.8) | 19 (42.2) | ＜0.001 |
| Liver injury | 30 (13.0) | 15 (8.1) | 15 (33.3) | ＜0.001 |
| Kidney injury | 17 (7.4) | 5 (2.7) | 12 (26.7) | ＜0.001 |
| Lower limb thrombosis | 4 (1.7) | 1 (0.5) | 3 (6.7) | 0.024 |
| Cerebral infarction | 8 (3.5) | 7 (3.7) | 1 (2.2) | 0.958 |
| Myocardial infarction | 4 (1.7) | 1 (0.5) | 3 (6.7) | 0.024 |
| Prognosis/(n，%) | ||||
| Survival | 209 (90.5) | 183 (98.4) | 26 (57.8) | ＜0.001 |
| Death | 22 (9.5) | 3 (1.6) | 19 (42.2) | |