Table 1. Summary of the reported cases with Enterococcus faecalis keratitis.
LP: light perception; IOL: intra-ocular lens; NA: not applicable; CF: counting fingers; PKP: penetrating keratoplasty; BCL: bandage contact lens; DMEK: Descemet membrane endothelial keratoplasty; DSEK: Descemet's stripping endothelial keratoplasty; SCL: scleral contact lens; AF: atrial fibrillation; CCF: congestive cardiac failure; CVA: cerebrovascular attack; AIDS: acquired immune deficiency syndromes
Case | Age (y) | Sex | Presenting visual acuity | Social history | Past medical history | Contact lens wearer | Past ocular history | Topical drops | Outcome | Culture results | Polymicrobial |
Lee and Lee, 2004 [1] | 67 | F | LP | NA | Diabetes mellitus | No | Phaco/IOL, endophthalmitis | None | Intravitreal vancomycin, amikacin, and amphotericin; second intravitreal injection on vancomycin, ceftazidime, and dexamethasone; third intravitreal injection of vancomycin and dexamethasone; topical vancomycin and fortified amikacin. Vitreous opacity resolved but corneal opacity and neovascularisation remained | E. faecalis | No |
Subashini et al., 2007 [6] | 30 | F | CF | NA | NA | No | Injury to the eye with fingernail | Ofloxacin | Resolved with a remaining corneal scar with topical vancomycin | E. faecalis | No |
Sherman et al., 1992 [7] | 61 | M | 20/400 | NA | NA | BCL | PKP, herpetic keratouveitis | None | Resolved on vancomycin and gentamicin | E. faecalis | No |
Sudana et al., 2021 [8] | 64 | M | 20/600 | NA | NA | No | DMEK, pseudophakia | Presumed topical steroids (post-op graft patient but steroids not specifically mentioned in report) | Topical vancomycin, removal of DMEK, new DSEK | E. faecalis | No |
Peng et al., 2009 [9] | 23 | F | 20/50 | Works as a pet groomer | NA | No | No | None | Cefazolin sodium, amikacin, ciprofloxacin, vancomycin, epithelial debridement | E. faecalis | No |
Lam et al., 1993 [10] | 65 | F | NA | NA | NA | BCL | PKP, endophthalmitis, alkali burns, cataract extraction, cyclocryotherapy for glaucoma | None | Fortified vancomycin, PKP | E. faecalis | No |
Lam et al., 1993 [10] | 88 | F | CF | NA | NA | No | PKP, amblyopia | None | Fortified vancomycin, PKP, extracapsular cataract extraction, IOL implantation | E. faecalis | No |
Rau et al., 2008 [11] | 17 | F | 20/200 | NA | None | Yes, SCL | None | None | Resolved on moxifloxacin | B. cereus, E. faecalis, K. pneumoniae | Yes |
Rau et al., 2008 [11] | 21 | F | 20/40 | NA | None | Yes, SCL | None | None | Resolved on moxifloxacin | P. aeruginosa, K. pneumoniae, E. faecalis | Yes |
Rau et al., 2008 [11] | 85 | M | HM | NA | Anemia, hypothyroidism, hypertension | No | Lamellar keratoplasty, two PKP, Mooren ulcer | Cyclosporine (2/2), artificial tears, tobramycin/ dexamethasone | PKP #3 | E. faecalis | No |
Rau et al., 2008 [11] | 58 | F | 20/25 | NA | None | Yes, SCL | Epithelial basement membrane dystrophy | Artificial tears | Resolved on moxifloxacin | E. faecalis Coagulase-negative S. aureus | Yes |
Rau et al., 2008 [11] | 55 | F | NA | NA | NA | Yes, SCL | None | NA | PKP | E. faecalis | No |
Rau et al., 2008 [11] | 73 | M | NA | NA | Bladder cancer | No | PKP | NA | NA | E. faecalis | No |
Rau et al., 2008 [11] | 57 | F | NA | NA | None | Yes, SCL | None | None | Resolved on fortified vancomycin | E. faecalis | No |
Rau et al., 2008 [11] | 89 | F | NA | NA | None | No | AMD | None | Resolved on fortified vancomycin | E. faecalis | No |
Rau et al., 2008 [11] | 23 | F | 20/60 | NA | None | Yes, SCL | None | None | Resolved on fortified vancomycin, ciprofloxacin | P. aeruginosa, E. faecalis, S. marcescens | Yes |
Rau et al., 2008 [11] | 85 | F | 5/200 | NA | Hypercholesterolemia | Yes, SCL | Cataract extraction | Timoptic 0.5% | Resolved on ofloxacin | E. faecalis | No |
Rau et al., 2008 [11] | 41 | F | CF | NA | None | No | Entropion | None | Resolved on moxifloxacin | E. faecalis, S. aureus | Yes |
Rau et al., 2008 [11] | 49 | M | 20/30 | NA | AIDS | No | Foreign body removal | None | Resolved on ofloxacin | E. faecalis | No |
Rau et al., 2008 [11] | 98 | F | CF | NA | AF, CCF, CVA, ovarian cancer, anemia, pacemaker | No | Entropion | None | PKP | E. faecalis | No |
Rau et al., 2008 [11] | 74 | F | 20/300 | NA | Schizophrenia, depression, paranoia, osteoporosis, hypothyroidism | No | Grave's ophthalmopathy, lagophthalmos | Pred Forte, Polytrim, Polysporin | Resolved on ciprofloxacin | E. faecalis, S. sciuri Corynebacterium species | Yes |
Rau et al., 2008 [11] | 37 | F | CF | NA | Migraine, appendectomy | Yes, SCL | Keratoconus | None | Resolved on fortified tobramycin and cefazolin | E. faecalis | No |