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. 2024 Jun 24;12(7):1397. doi: 10.3390/biomedicines12071397

Table 4.

Pooled proportions for the association of the different anomalies in fetuses with MCD detected at ultrasound.

Outcome Studies (n) Fetuses (n/N) Pooled Proportions
% (95% CI)
I2 (%)
Associated CNS anomalies at ultrasound 9 123/130 93.79 (89.11–97.23) 0
Associated extra-CNS anomalies at ultrasound 8 49/125 38.84 (27.32–53.08) 55.9
Isolated findings at ultrasound 9 7/130 6.21 (2.77–10.89) 0
Ventriculomegaly 9 8/130 6.20 (0.69–16.67) 73.3
Midline anomalies 9 1/130 10.17 (1.80–24.24) 0
Posterior fossa anomalies 9 12/130 2.24 (0.43–5.41) 79
Multiple anomalies 9 117/130 82.63 (65.55–94.69) 80.6

CNS, central nervous system.