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. 1994 Nov;51(11):784–785. doi: 10.1136/oem.51.11.784

Polypropylene production workers and colorectal cancer in Germany: a brief report.

R Kaleja 1, L Horbach 1, J Amsel 1
PMCID: PMC1128105  PMID: 7849858

Abstract

OBJECTIVE--A retrospective cohort study of 640 male polypropylene production workers in Germany was performed to evaluate the reported association between colorectal cancer and polypropylene. METHOD--The follow up period was 1956 to 1990. Expected numbers of cancers were derived from incidence rates adjusted for age and calendar year from the Saarland cancer registry. RESULTS--Three colorectal cancers were identified compared with 4.0 expected (standardised incidence ration (SIR) = 0.75, 95% confidence interval (95% CI): 0.15-2.19). For total cancers there were 27 cases in the cohort compared with 35.4 expected (SIR = 0.76, 95% CI: 0.50-1.11). DISCUSSION--These results do not support earlier reports of a link between polypropylene production and colorectal cancer, but are consistent with a number of recent investigations of polypropylene production workers that have reported no association with risk of colorectal cancer. Due to the small size of this and other similar studies, however, a small to moderate increase in risk cannot be ruled out.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Acquavella J. F., Douglass T. S., Phillips S. C. Evaluation of excess colorectal cancer incidence among workers involved in the manufacture of polypropylene. J Occup Med. 1988 May;30(5):438–442. doi: 10.1097/00043764-198805000-00012. [DOI] [PubMed] [Google Scholar]
  2. Acquavella J. F., Owen C. V. Assessment of colorectal cancer incidence among polypropylene pilot plant employees. J Occup Med. 1990 Feb;32(2):127–130. [PubMed] [Google Scholar]
  3. Bouskill J. Absence of risk of colorectal cancer among workers at a UK polypropylene production plant. Occup Environ Med. 1994 Nov;51(11):786–786. doi: 10.1136/oem.51.11.786. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Christie D., Robinson K., Gordon I., Bisby J. A prospective study in the Australian petroleum industry. II. Incidence of cancer. Br J Ind Med. 1991 Aug;48(8):511–514. doi: 10.1136/oem.48.8.511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldberg M. S., Thériault G. Retrospective cohort study of workers of a synthetic textiles plant in Quebec: II. Colorectal cancer mortality and incidence. Am J Ind Med. 1994 Jun;25(6):909–922. doi: 10.1002/ajim.4700250613. [DOI] [PubMed] [Google Scholar]
  6. Lewis R. J., Schnatter A. R., Lerman S. E. Colorectal cancer incidence among polypropylene manufacturing workers. An update. J Occup Med. 1994 Jun;36(6):652–659. [PubMed] [Google Scholar]
  7. Vobecky J., Devroede G., Caro J. Risk of large-bowel cancer in synthetic fiber manufacture. Cancer. 1984 Dec 1;54(11):2537–2542. doi: 10.1002/1097-0142(19841201)54:11<2537::aid-cncr2820541138>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]

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