Abstract
OBJECTIVE: To investigate whether the sex ratio of children varies between fathers of different occupations. METHODS: The sex ratio (the ratio of the number of boys to the number of girls at birth) was calculated in relation to paternal occupation in the cohort of all 253,433 live births in Cumbria, north west England, from 1950-89. Exact binomial confidence intervals were used to estimate whether the sex ratio in each occupational category was significantly different from that for the rest of the cohort. RESULTS: There were fewer occupational categories with significantly different sex ratios at the 5% level than expected by chance alone, assuming the same binomial distribution of sexes at birth within each paternal occupation. CONCLUSIONS: Significant variation of the sex ratio with fathers' occupations was not found. There is some evidence that the sex ratio shows less variance than expected under a binomial model which assumes independence of the sex of each child; a possible explanation of this may be parental preference for limiting family size after children of both sexes have been born or some other factor which results in children within a family being more likely to be of both sexes rather than the same sex.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abernethy K., Bradley B. E., Dankmyer B., Connerton P., England M. J., Goldsmith M., Mortimer J., Maher W. B., Halvorson G. C., Simmons H. E. Predicting progress and pitfalls in 1996. Discussion. Bus Health. 1996 Jan;14(1):16-7, 20, 22-4. [PubMed] [Google Scholar]
- BERNSTEIN M. E. Action of genes affecting secondary sex ratio in man. Science. 1951 Aug 17;114(2955):181–182. doi: 10.1126/science.114.2955.181-a. [DOI] [PubMed] [Google Scholar]
- Dickinson H. O., Parker L., Binks K., Wakeford R., Smith J. The sex ratio of children in relation to paternal preconceptional radiation dose: a study in Cumbria, northern England. J Epidemiol Community Health. 1996 Dec;50(6):645–652. doi: 10.1136/jech.50.6.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dickinson H., Parker L. Do alcohol and lead change the sex ratio? J Theor Biol. 1994 Aug 7;169(3):313–315. doi: 10.1006/jtbi.1994.1152. [DOI] [PubMed] [Google Scholar]
- Easterbrook P. J., Berlin J. A., Gopalan R., Matthews D. R. Publication bias in clinical research. Lancet. 1991 Apr 13;337(8746):867–872. doi: 10.1016/0140-6736(91)90201-y. [DOI] [PubMed] [Google Scholar]
- Edwards A. W. Sex-ratio data analysed independently of family limitation. Ann Hum Genet. 1966 May;29(4):337–347. doi: 10.1111/j.1469-1809.1966.tb00529.x. [DOI] [PubMed] [Google Scholar]
- James W. H. Sex ratio of offspring as a criterion of occupational hazard, with reference to welding. Scand J Work Environ Health. 1994 Dec;20(6):466–467. doi: 10.5271/sjweh.1373. [DOI] [PubMed] [Google Scholar]
- Lloyd M. M., Lyster W. R., Lloyd O. L. Birth sex ratios and prostatic cancer in butchers. Lancet. 1987 Mar 7;1(8532):561–561. doi: 10.1016/s0140-6736(87)90201-7. [DOI] [PubMed] [Google Scholar]
- Lyster W. R. Altered sex ratio in children of divers. Lancet. 1982 Jul 17;2(8290):152–152. doi: 10.1016/s0140-6736(82)91113-8. [DOI] [PubMed] [Google Scholar]
- Lyster W. R., Lloyd M. M., Lloyd O. L. Low sex ratio in children of men in alcohol-related occupations. J R Coll Physicians Lond. 1987 Oct;21(4):280–281. [PMC free article] [PubMed] [Google Scholar]
- Milham S., Jr Unusual sex ratio of births to carbon setter fathers. Am J Ind Med. 1993 May;23(5):829–831. doi: 10.1002/ajim.4700230516. [DOI] [PubMed] [Google Scholar]
- Shaw G. M., Malcoe L. H., Croen L. A., Smith D. F. An assessment of error in parental occupation from the birth certificate. Am J Epidemiol. 1990 Jun;131(6):1072–1079. doi: 10.1093/oxfordjournals.aje.a115599. [DOI] [PubMed] [Google Scholar]
- Wyatt R., Wilson A. M. Children of anaesthetists. Br Med J. 1973 Mar 17;1(5854):675–675. doi: 10.1136/bmj.1.5854.675-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
