Skip to main content
The Western Journal of Medicine logoLink to The Western Journal of Medicine
. 1974 Nov;121(5):374–381.

Part II – Roentgenologic Aspects

Roy A Filly 1,2, Gerald W Friedland 1,2, Duncan E Govan 1,2, William R Fair 1,2
PMCID: PMC1129607  PMID: 4460379

Abstract

Roentgen findings in 107 girls under the age of ten years who had proven recurrent urinary tract infections were analyzed. From the excretory urograms done on these children, renal and pelvocalyceal outlines were accurately traced. Subsequently, renal length and parenchymal thickness at multiple points were measured. The presence or absence and grade of reflux were determined by voiding cystourethrography. Finally, the clinical history was correlated with the roentgen findings.

With three exceptions, scarring and clubbing in the presence of infection occurred only in refluxing renal units. Kidneys exposed to a higher grade of reflux more frequently showed scarring and clubbing (p<0.001). Seventeen out of 40 renal units either developed or had increase in clubbing and scarring while the patients were being followed. After surgical correction of reflux, 16 of 24 previously clubbed and scarred kidneys showed progression of the lesions, usually within 24 months after operation. All children whose kidneys showed progression after surgical operation had experienced an episode of acute urinary infection with chills and fever before operation.

No significant difference existed in the age at clinical onset of infection in patients with ureteral reflux with or without roentgen evidence of clubbing and scarring. This study documents the close relationship between clubbing and scarring and reflux in the presence of urinary infection in infants and children.

Full text

PDF
374

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Altman D. H., Lavastida M. T., Litt R. E., Greenberg L. A. The roentgen evaluation of the urinary tract following treatment for vesicoureteral reflux. Radiology. 1969 Sep;93(3):593–597. doi: 10.1148/93.3.593. [DOI] [PubMed] [Google Scholar]
  2. Amar A. D. Calicotubular backflow with vesicoureteral reflux. Relation to pyelonephritis. JAMA. 1970 Jul 13;213(2):293–294. [PubMed] [Google Scholar]
  3. Blank E. Calicectasis and renal scars in children. J Urol. 1973 Aug;110(2):255–258. doi: 10.1016/s0022-5347(17)60180-0. [DOI] [PubMed] [Google Scholar]
  4. Blank E., Girdany B. R. Prognosis with vesicoureteral reflux. Pediatrics. 1971 Nov;48(5):782–787. [PubMed] [Google Scholar]
  5. Brodeur A. E., Goyer R. A., Melick W. A potential hazard of barium cystography. Radiology. 1965 Dec;85(6):1080–1084. doi: 10.1148/85.6.1080. [DOI] [PubMed] [Google Scholar]
  6. Dwoskin J. Y., Perlmutter A. D. Vesicoureteral reflux in children: a computerized review. J Urol. 1973 May;109(5):888–890. doi: 10.1016/s0022-5347(17)60572-x. [DOI] [PubMed] [Google Scholar]
  7. Fair W. R., Govan D. E., Friedland G. W., Filly R. A. Urinary tract infections in children. Part I-- Young girls with non-refluxing ureters. West J Med. 1974 Nov;121(5):366–373. [PMC free article] [PubMed] [Google Scholar]
  8. Filly R., Friedland G. W., Govan D. E., Fair W. R. Development and progression of clubbing and scarring in children with recurrent urinary tract infections. Radiology. 1974 Oct;113(1):145–153. doi: 10.1148/113.1.145. [DOI] [PubMed] [Google Scholar]
  9. Friedland G. W., Filly R., Brown B. W. Distance of upper pole calyx to spine and lower pole calyx to ureter as indicators of parenchymal loss in children. Pediatr Radiol. 1974 Apr 5;2(1):29–37. doi: 10.1007/BF00972844. [DOI] [PubMed] [Google Scholar]
  10. Govan D. E., Fair W. R., Friedland G. W., Filly R. A. Urinary tract infections in children. Part III--Treatment of ureterovesical reflux. West J Med. 1974 Nov;121(5):382–389. [PMC free article] [PubMed] [Google Scholar]
  11. HODSON C. J. The radiological diagnosis of pyelonephritis. Proc R Soc Med. 1959 Aug;52:669–672. doi: 10.1177/003591575905200819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HODSON J. PYELONEPHRITIS IN CHILDREN. Ann Radiol (Paris) 1964;7:355–359. [PubMed] [Google Scholar]
  13. Hodson C. J. Letter: Radiology now: ureteric reflux. Br J Radiol. 1974 Feb;47(554):153–153. doi: 10.1259/0007-1285-47-554-153-a. [DOI] [PubMed] [Google Scholar]
  14. Hodson C. J. The radiological contribution toward the diagnosis of chronic pyelonephritis. Radiology. 1967 May;88(5):857–871. doi: 10.1148/88.5.857. [DOI] [PubMed] [Google Scholar]
  15. Hodson C. J., Wilson S. Natural History of Chronic Pyelonephritic Scarring. Br Med J. 1965 Jul 24;2(5455):191–194. doi: 10.1136/bmj.2.5455.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Kendall A. R., Karafin L. Urinary tract infection in children: fact and fantasy. J Urol. 1972 Jun;107(6):1068–1072. doi: 10.1016/s0022-5347(17)61210-2. [DOI] [PubMed] [Google Scholar]
  17. Lyon R. P. Renal arrest. J Urol. 1973 Apr;109(4):707–710. doi: 10.1016/s0022-5347(17)60521-4. [DOI] [PubMed] [Google Scholar]
  18. MacGregor M. Pyelonephritis lenta. Consideration of childhood urinary infection as the forerunner of renal insufficiency in later life. Arch Dis Child. 1970 Apr;45(240):159–172. doi: 10.1136/adc.45.240.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. McAlister W. H., Cacciarelli A., Shackelford G. D. Complications associated with cystography in children. Radiology. 1974 Apr;111(1):167–172. doi: 10.1148/111.1.167. [DOI] [PubMed] [Google Scholar]
  20. Scott J. E., Stansfeld J. M. Ureteric reflux and kidney scarring in children. Arch Dis Child. 1968 Aug;43(230):468–470. doi: 10.1136/adc.43.230.468. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Smellie J. M. Acute urinary tract infection in children. Br Med J. 1970 Oct 10;4(5727):97–100. doi: 10.1136/bmj.4.5727.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Vermillion C. D., Heale W. F. Position and configuration of the ureteral orifice and its relationship to renal scarring in adults. J Urol. 1973 Apr;109(4):579–584. doi: 10.1016/s0022-5347(17)60484-1. [DOI] [PubMed] [Google Scholar]
  23. Welch T. R., Nogrady M. B., Outerbridge E. W. Roentgenologic sequelae of neonatal septicemia and urinary tract infection. Am J Roentgenol Radium Ther Nucl Med. 1973 May;118(1):28–38. doi: 10.2214/ajr.118.1.28. [DOI] [PubMed] [Google Scholar]

Articles from Western Journal of Medicine are provided here courtesy of BMJ Publishing Group

RESOURCES