Table 3.
Diagnostic reliability of PAC and PVC frequencies compared with the overall 14-day average
| 24 h recording | 72 h recording | 7-Day recording | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | |
| Premature atrial contractions | ||||||||||||
| As daily frequencies | ||||||||||||
| <100 | 95.5 (94.9–96.1) | 83.7 (82.4–84.4) | 87.6 (86.6–88.5) | 94.0 (93.1–94.8) | 96.4 (95.8–96.9) | 88.9 (87.8–89.8) | 95.4 (94.6–96.1) | 91.2 (90.4–92.0) | 98.0 (97.6–98.4) | 93.6 (92.7–94.3) | 94.8 (94.1–95.4) | 97.5 (97.0–98.0) |
| 100–499 | 63.3 (61.1–65.5) | 92.3 (91.7–93.0) | 70.9 (68.6–73.0) | 89.5 (88.8–90.3) | 72.2 (70.1–74.2) | 93.8 (93.2–94.4) | 77.5 (75.5–79.5) | 92.0 (91.3–92.6) | 83.5 (81.7–85.1) | 96.4 (95.9–96.8) | 87.2 (85.5–88.7) | 95.2 (94.6–95.7) |
| 500–999 | 33.3 (29.4–37.4) | 96.6 (96.2–97.0) | 41.6 (37.0–46.3) | 95.2 (94.7–95.7) | 42.6 (38.5–46.9) | 96.6 (96.2–97.0) | 47.6 (43.1–52.1) | 95.9 (95.4–96.3) | 59.4 (55.1–63.5) | 97.4 (97.1–97.8) | 62.6 (58.3–66.8) | 97.1 (96.7–97.4) |
| 1000–4999 | 63.6 (60.3–66.8) | 96.8 (96.4–97.2) | 70.5 (67.2–73.6) | 95.7 (95.2–96.1) | 70.2 (67.1–73.2) | 97.1 (96.7–97.5) | 74.5 (71.4–77.4) | 96.4 (96.0–96.8) | 81.2 (78.4–83.7) | 98.3 (97.9–98.5) | 84.9 (82.3–87.2) | 97.7 (97.4–98.1) |
| 5000–9999 | 48.4 (41.5–55.3) | 98.7 (98.5–99.9) | 50.2 (43.2–57.3) | 98.6 (98.4–98.9) | 54.0 (47.0–60.8) | 98.9 (98.6–99.1) | 56.1 (49.0–63.0) | 98.8 (98.5–99.0) | 73.2 (66.8–79.1) | 99.2 (98.9–99.4) | 70.0 (63.5–75.9) | 99.3 (99.1–99.5) |
| ≥10 000 | 76.6 (70.1–80.4) | 99.3 (99.1–99.5) | 73.3 (66.7–79.2) | 99.4 (99.2–99.6) | 83.2 (77.3–88.2) | 99.5 (99.4–99.7) | 81.6 (75.5–86.7) | 99.6 (99.4–99.7) | 88.8 (83.6–92.9) | 99.7 (99.6–99.8) | 88.8 (83.6–92.9) | 99.7 (99.6–99.8) |
| As % of total beats | ||||||||||||
| 0–0.09% | 95.3 (94.6–95.9) | 85.6 (84.5–86.7) | 88.3 (87.3–89.2) | 94.1 (93.3–94.9) | 98.6 (98.2–98.9) | 82.1 (80.9–83.3) | 86.3 (85.3–87.2) | 98.0 (97.5–98.5) | 93.9 (93.1–94.6) | 96.2 (95.6–96.8) | 96.6 (96.0–97.1) | 93.2 (92.4–94.0) |
| 0.1–0.99% | 71.9 (70.1–73.6) | 92.5 (91.8–93.1) | 80.5 (78.8–82.1) | 88.4 (87.5–89.2) | 70.6 (68.7–72.4) | 94.0 (93.4–94.6) | 83.6 (81.9–85.9) | 88.1 (87.2–88.9) | 88.3 (87.0–89.6) | 93.9 (93.2–94.5) | 86.2 (84.8–87.5) | 94.9 (94.3–95.5) |
| 1–9.9% | 71.6 (68.9–74.2) | 96.9 (96.5–97.3) | 79.1 (76.5–81.5) | 95.4 (94.9–95.9) | 73.1 (70.4–75.6) | 98.1 (97.8–98.4) | 86.3 (84.0–88.4) | 95.7 (95.2–96.2) | 87.4 (85.4–89.3) | 97.8 (97.4–98.1) | 86.6 (84.5–88.5) | 97.9 (97.6–98.3) |
| ≥10% | 82.6 (76.7–87.5) | 99.2 (99.0–99.4) | 72.8 (66.6–78.4) | 99.6 (99.4–99.7) | 65.7 (58.8–72.1) | 99.9 (99.8–99.9) | 92.5 (87.0–96.2) | 99.1 (98.9–99.3) | 96.1 (92.5–98.3) | 99.3 (99.1–99.4) | 77.1 (71.5–82.1) | 99.9 (99.8–100) |
| Premature ventricular contractions | ||||||||||||
| As daily frequencies | ||||||||||||
| <100 | 96.0 (95.4–96.5) | 84.0 (82.6–85.2) | 90.9 (90.1–91.6) | 92.6 (91.6–93.6) | 96.9 (96.3–97.3) | 88.6 (87.4–89.7) | 93.4 (92.7–94.0) | 94.4 (93.5–95.2) | 97.8 (97.4–98.2) | 93.1 (92.1–94.0) | 95.9 (95.4–96.4) | 96.2 (95.5–96.9) |
| 100–499 | 60.1 (57.5–62.6) | 93.7 (93.1–94.3) | 67.1 (64.5–69.7) | 91.7 (91.0–92.3) | 70.1 (67.7–72.4) | 95.1 (94.6–95.6) | 75.5 (73.1–77.7) | 93.7 (93.1–94.3) | 82.1 (80.0–84.1) | 96.6 (96.2–97.0) | 83.9 (81.8–85.7) | 96.2 (95.7–96.6) |
| 500–999 | 36.5 (32.3–40.8) | 96.9 (96.5–97.3) | 43.9 (39.1–48.7) | 95.9 (95.4–96.3) | 51.2 (46.7–55.6) | 97.3 (96.9–97.7) | 55.8 (51.1–60.3) | 96.8 (96.4–97.2) | 65.5 (61.2–69.6) | 98.2 (97.9–98.5) | 70.8 (66.4–74.8) | 97.7 (97.4–98.1) |
| 1000–4999 | 66.8 (63.4–70.1) | 97.4 (97.0–97.8) | 72.8 (69.3–76.0) | 96.6 (96.2–97.0) | 75.4 (72.2–78.4) | 98.0 (97.7–98.3) | 79.7 (76.6–82.5) | 97.5 (97.1–97.8) | 84.1 (81.4–86.6) | 98.8 (98.5–99.0) | 87.8 (85.2–90.0) | 98.4 (98.0–98.6) |
| 5000–9999 | 55.3 (47.7–62.7) | 98.7 (98.4–98.9) | 48.5 (41.5–55.6) | 99.0 (98.8–99.2) | 55.3 (47.7–62.7) | 99.0 (98.7–99.2) | 54.4 (46.9–61.8) | 99.0 (98.8–99.2) | 75.4 (68.4–81.5) | 99.3 (99.1–99.5) | 71.4 (64.4–77.8) | 99.5 (99.3–99.6) |
| ≥10 000 | 79.4 (72.7–85.2) | 99.6 (99.4–99.7) | 80.3 (73.6–86.0) | 99.6 (99.4–99.7) | 82.3 (75.8–87.6) | 99.6 (99.4–99.7) | 80.4 (73.9–86.0) | 99.6 (99.5–99.7) | 86.9 (80.9–91.5) | 99.7 (99.6–99.8) | 86.4 (80.4–91.1) | 99.7 (99.6–99.8) |
| As % of total beats | ||||||||||||
| 0–0.99% | 98.8 (98.5–99.1) | 80.5 (79.1–81.9) | 89.1 (88.3–89.3) | 97.7 (97.0–98.2) | 98.5 (98.1–98.8) | 83.8 (82.4–85.0) | 90.7 (89.9–91.5) | 97.2 (96.5–97.8) | 95.9 (95.4–96.5) | 95.4 (94.6–96.1) | 97.1 (96.6–97.6) | 93.6 (92.7–94.4) |
| 0.1–0.99% | 70.9 (68.8–72.9) | 94.2 (93.6–94.7) | 79.2 (77.2–81.1) | 91.2 (90.4–91.8) | 73.1 (71.1–75.1) | 95.4 (94.8–95.9) | 83.2 (81.3–84.9) | 91.9 (91.2–92.5) | 85.8 (84.1–87.3) | 95.9 (95.4–96.4) | 86.7 (85.1–88.2) | 95.6 (95.0–96.1) |
| 1–9.9% | 76.1 (73.3–78.7) | 97.7 (97.3–98.8) | 81.9 (79.3–84.3) | 96.7 (96.3–97.1) | 75.4 (72.6–78.0) | 98.7 (98.4–98.9) | 88.8 (86.5–90.8) | 96.6 (96.2–97.0) | 88.8 (86.7–90.7) | 97.9 (97.6–98.3) | 85.7 (83.4–87.8) | 98.4 (98.1–98.7) |
| ≥10% | 82.3 (76.0–87.6) | 99.4 (99.2–99.6) | 76.0 (69.4–81.8) | 99.6 (99.4–99.7) | 71.8 (64.7–78.2) | 99.9 (99.8–100) | 95.6 (90.6–98.4) | 99.4 (99.2–99.5) | 97.2 (93.7–99.1) | 99.4 (99.2–99.5) | 77.2 (71.2–82.5) | 99.9 (99.9–100) |
NPV, negative predictive value; PPV, positive predictive value.