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. 2024 Aug 6;22:390. doi: 10.1186/s12964-024-01772-x

Correction: RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway

Jiang Shao 1, Yuxiao Meng 1, Kaikun Yuan 1, Qiaowei Wu 1, Shiyi Zhu 1, Yuchen Li 1, Pei Wu 1, Jiaolin Zheng 2,, Huaizhang Shi 1,
PMCID: PMC11301847  PMID: 39107840

Correction: Cell Commun Signal 21, 264 (2023)

10.1186/s12964-023-01274-2

Following publication of the original article [1], the authors reported an error in Fig. 1A, whereby the western blot band of β-tubulin in Fig. 1A was misused unintentionally, which overlapped with the band in Fig. 4A. This error occurred during the figure preparation.

Fig. 1.

Fig. 1

Expression changes of cGAS and microglial localization. A, B Representative Western blot bands of time course and quantitative analysis for cGAS. n = 6 per group. *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. ns, not significant. C Representative images of double immunofluorescence staining for cGAS (green) with microglia (Iba1, red) at 24 h after SAH. Cell nuclei were counterstained with DAPI (blue). Scale bar = 50 μm. n = 6 per group

The incorrect Fig. 1 is

The correct Fig. 1 is:

Fig. 1.

Fig. 1

Expression changes of cGAS and microglial localization. A, B Representative Western blot bands of time course and quantitative analysis for cGAS. n = 6 per group. *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. ns, not significant. C Representative images of double immunofluorescence staining for cGAS (green) with microglia (Iba1, red) at 24 h after SAH. Cell nuclei were counterstained with DAPI (blue). Scale bar = 50 μm. n = 6 per group

Further to this, please note Fig. 1A for β-tubulin related to Fig. 1A in the original supplementary file 2 was also incorrect. The complete updated supplementary file is provided as “Supplementary Material 2” in this correction article.

Electronic supplementary material

Below is the link to the electronic supplementary material.

12964_2024_1772_MOESM1_ESM.pdf (936.4KB, pdf)

Supplementary Material 2: Uncropped Western bot gel images.

Footnotes

The online version of the original article can be found at 10.1186/s12964-023-01274-2.

Publisher’s Note

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Contributor Information

Jiaolin Zheng, Email: zhengjiaolin82@163.com.

Huaizhang Shi, Email: shihuaizhang@hrbmu.edu.cn, Email: huaizhangshi@163.com, Email: huaizhangshi@126.com.

References

  • 1.Shao J, Meng Y, Yuan K, et al. RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway. Cell Commun Signal. 2023;21:264. 10.1186/s12964-023-01274-2. 10.1186/s12964-023-01274-2 [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

12964_2024_1772_MOESM1_ESM.pdf (936.4KB, pdf)

Supplementary Material 2: Uncropped Western bot gel images.


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