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. 1992 Jan 1;281(Pt 1):41–43. doi: 10.1042/bj2810041

Induction of peroxisomal beta-oxidation genes by retinoic acid in cultured rat hepatocytes.

R Hertz 1, J Bar-Tana 1
PMCID: PMC1130637  PMID: 1346245

Abstract

Retinoic acid is reported here to induce peroxisomal beta-oxidation activities in cultured rat hepatocytes, with a concomitant increase in respective peroxisomal mRNAs. The concentrations of retinoic acid required for inducing liver peroxisomal acyl-CoA oxidase were similar to those required for inducing liver transglutaminase. A putative 5'-flanking response element for retinoic acid may be found within the enhancer region involved in the induction of peroxisomal genes by xenobiotic amphipathic carboxylates.

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Selected References

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