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. 1992 Jan 1;281(Pt 1):137–142. doi: 10.1042/bj2810137

Purification of an Arg-Gly-Asp selective matrix receptor from brain synaptic plasma membranes.

B A Bahr 1, G Lynch 1
PMCID: PMC1130651  PMID: 1731748

Abstract

Brain synaptic plasma membranes specifically associated with matrix protein monolayers containing the Arg-Gly-Asp sequence recognized by integrin-type adhesion receptors. Experiments using fibronectin affinity chromatography to identify the synaptosomal receptors responsible for this interaction led to the purification of a 55 kDa Arg-Gly-Asp recognition protein that is labelled by antibodies against the alpha 5 beta 1 integrin.

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