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. 1990 Apr 1;267(1):257–260. doi: 10.1042/bj2670257

Use of the intact mouse skeletal-muscle preparation for metabolic studies. Evaluation of the model.

E van Breda 1, H A Keizer 1, J F Glatz 1, P Geurten 1
PMCID: PMC1131274  PMID: 2183795

Abstract

1. We examined the isolated mouse skeletal-muscle model in vitro, commonly used by many investigators, for its suitability for metabolic studies. 2. Despite the fact that pH, O2 saturation, osmolality and the release of the enzyme creatine kinase remained stable, histochemical studies showed large cores devoid of glycogen, suggesting that the incubated muscle had lost its viability. 3. This study indicates that caution should be exercised when interpreting the results of studies with intact isolated mouse muscles.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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