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[Preprint]. 2024 Aug 17:2024.08.12.24311729. [Version 1] doi: 10.1101/2024.08.12.24311729

Figure 6. Global correlation changes (GCOR) associated with N2O exposure.

Figure 6.

Top: Bar graph of effect size changes in functional connectivity over time. Similar to the individual seed -> voxel maps, functional connectivity changes were in opposite directional following N2O exposure: CNTL participants (yellow bars) demonstrated increased functional connectivity and TRD participants (red bars) decreased functional connectivity. Bottom: GCOR changes associated with N2O exposure in the combined sample (CNTL + TRD) included bilateral dorsal anterior cingulate, frontal poles, left dorsolateral prefrontal cortex, and right superior frontal gyrus and orbitofrontal cortex.