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. 1993 Sep 1;294(Pt 2):487–490. doi: 10.1042/bj2940487

Expression of the calsequestrin gene in chicken cerebellum Purkinje neurons.

P Volpe 1, L Gorza 1, M Brini 1, R Sacchetto 1, S Ausoni 1, D O Clegg 1
PMCID: PMC1134480  PMID: 8373363

Abstract

Intracellular rapidly exchanging Ca2+ stores are identified and defined in terms of intralumenal low-affinity, high-capacity Ca(2+)-binding proteins, of which calsequestrin (CS) is the prototype in striated muscles. In chicken striated muscles, there is a single gene for CS [Choi and Clegg (1990) Dev. Biol. 142, 169-177]. In the chicken brain, the gene for CS was found to be selectively expressed in Purkinje neurons, as judged by Northern blotting, in situ hybridization and immunocytochemistry. The synthetic machinery for CS was found to be restricted to the cell body, i.e. excluded from dendrites and axon.

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Selected References

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