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. 1988 Oct 1;255(1):79–83. doi: 10.1042/bj2550079

The structure of the human glutathione S-transferase pi gene.

I G Cowell 1, K H Dixon 1, S E Pemble 1, B Ketterer 1, J B Taylor 1
PMCID: PMC1135192  PMID: 3196325

Abstract

The human glutathione S-transferase pi gene has been isolated from a cosmid library. The gene spans approximately 3 kb, is interrupted by six introns and the region around its 5' end has the high G + C and CpG content typical of an HTF (HpaII tiny fragment) island. In addition to a TATA box at position -28 relative to the transcription initiation site and two G + C boxes (GGGCGG), the promoter contains a sequence motif matching the phorbol ester- and ras-responsive element from the polyoma virus enhancer.

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Selected References

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