Skip to main content
NCBI home page
Biochemical Journal logoLink to Biochemical Journal
. 1989 Jan 15;257(2):313–320. doi: 10.1042/bj2570313

Metabolic interactions between eicosanoids in blood and vascular cells.

M Lagarde 1, N Gualde 1, M Rigaud 1
PMCID: PMC1135582  PMID: 2494983

Full text

PDF
313

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benjamin C. W., Hopkins N. K., Oglesby T. D., Gorman R. R. Agonist specific desensitization of leukotriene C4-stimulated PGI2 biosynthesis in human endothelial cells. Biochem Biophys Res Commun. 1983 Dec 28;117(3):780–787. doi: 10.1016/0006-291x(83)91665-0. [DOI] [PubMed] [Google Scholar]
  2. Billah M. M., Bryant R. W., Siegel M. I. Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2. J Biol Chem. 1985 Jun 10;260(11):6899–6906. [PubMed] [Google Scholar]
  3. Bordet J. C., Guichardant M., Lagarde M. Arachidonic acid strongly stimulates prostaglandin I3 (PGI3) production from eicosapentaenoic acid in human endothelial cells. Biochem Biophys Res Commun. 1986 Mar 13;135(2):403–410. doi: 10.1016/0006-291x(86)90009-4. [DOI] [PubMed] [Google Scholar]
  4. Bordet J. C., Guichardant M., Lagarde M. Hydroperoxides produced by n-6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds. Biochim Biophys Acta. 1988 Feb 19;958(3):460–468. doi: 10.1016/0005-2760(88)90232-9. [DOI] [PubMed] [Google Scholar]
  5. Bordet J. C., Lagarde M. Modulation of prostacyclin/thromboxane formation by molsidomine during platelet-endothelial cell interactions. Biochem Pharmacol. 1988 Oct 15;37(20):3911–3914. doi: 10.1016/0006-2952(88)90073-1. [DOI] [PubMed] [Google Scholar]
  6. Borgeat P., Fruteau de Laclos B., Picard S., Drapeau J., Vallerand P., Corey E. J. Studies on the mechanism of formation of the 5S, 12S-dihydroxy-6,8,10,14(E,Z,E,Z)-icosatetraenoic acid in leukocytes. Prostaglandins. 1982 May;23(5):713–724. doi: 10.1016/s0090-6980(82)80009-9. [DOI] [PubMed] [Google Scholar]
  7. Borgeat P., Samuelsson B. Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3213–3217. doi: 10.1073/pnas.76.7.3213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Boukhchache D., Lagarde M. Interactions between prostaglandin precursors during their oxygenation by human platelets. Biochim Biophys Acta. 1982 Nov 12;713(2):386–392. doi: 10.1016/0005-2760(82)90257-0. [DOI] [PubMed] [Google Scholar]
  9. Brotherton A. F., Hoak J. C. Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium. Proc Natl Acad Sci U S A. 1982 Jan;79(2):495–499. doi: 10.1073/pnas.79.2.495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Brotherton A. F., Macfarlane D. E., Hoak J. C. Prostacyclin biosynthesis in vascular endothelium is not inhibited by cyclic AMP. Studies with 3-isobutyl-1-methylxanthine and forskolin. Thromb Res. 1982 Dec 1;28(5):637–647. doi: 10.1016/0049-3848(82)90155-4. [DOI] [PubMed] [Google Scholar]
  11. Bryant R. W., Simon T. C., Bailey J. M. Role of glutathione peroxidase and hexose monophosphate shunt in the platelet lipoxygenase pathway. J Biol Chem. 1982 Dec 25;257(24):14937–14943. [PubMed] [Google Scholar]
  12. Buchanan M. R., Haas T. A., Lagarde M., Guichardant M. 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. J Biol Chem. 1985 Dec 25;260(30):16056–16059. [PubMed] [Google Scholar]
  13. Camp R. D., Fincham N. J. Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids. Br J Pharmacol. 1985 Aug;85(4):837–841. doi: 10.1111/j.1476-5381.1985.tb11082.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Campbell W. B., Falck J. R., Okita J. R., Johnson A. R., Callahan K. S. Synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells. Biochim Biophys Acta. 1985 Oct 23;837(1):67–76. doi: 10.1016/0005-2760(85)90086-4. [DOI] [PubMed] [Google Scholar]
  15. Capdevila J. H., Mosset P., Yadagiri P., Lumin S., Falck J. R. NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. Arch Biochem Biophys. 1988 Feb 15;261(1):122–133. doi: 10.1016/0003-9861(88)90111-7. [DOI] [PubMed] [Google Scholar]
  16. Capdevila J., Marnett L. J., Chacos N., Prough R. A., Estabrook R. W. Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. Proc Natl Acad Sci U S A. 1982 Feb;79(3):767–770. doi: 10.1073/pnas.79.3.767. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Chan C. C., Duhamel L., Ford-Hutchison A. Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig. J Invest Dermatol. 1985 Oct;85(4):333–334. doi: 10.1111/1523-1747.ep12276933. [DOI] [PubMed] [Google Scholar]
  18. Chang J., Blazek E., Kreft A. F., Lewis A. J. Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. Biochem Pharmacol. 1985 May 1;34(9):1571–1575. doi: 10.1016/0006-2952(85)90701-4. [DOI] [PubMed] [Google Scholar]
  19. Claeys M., Kivits G. A., Christ-Hazelhof E., Nugteren D. H. Metabolic profile of linoleic acid in porcine leukocytes through the lipoxygenase pathway. Biochim Biophys Acta. 1985 Oct 23;837(1):35–51. doi: 10.1016/0005-2760(85)90083-9. [DOI] [PubMed] [Google Scholar]
  20. Conti P., Reale M., Cancelli A., Angeletti P. U. Lipoxin A augments release of thromboxane from human polymorphonuclear leukocyte suspensions. FEBS Lett. 1987 Dec 10;225(1-2):103–108. doi: 10.1016/0014-5793(87)81139-0. [DOI] [PubMed] [Google Scholar]
  21. Cramer E. B., Pologe L., Pawlowski N. A., Cohn Z. A., Scott W. A. Leukotriene C promotes prostacyclin synthesis by human endothelial cells. Proc Natl Acad Sci U S A. 1983 Jul;80(13):4109–4113. doi: 10.1073/pnas.80.13.4109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Croset M., Guichardant M., Lagarde M. Different metabolic behavior of long-chain n-3 polyunsaturated fatty acids in human platelets. Biochim Biophys Acta. 1988 Jul 22;961(2):262–269. doi: 10.1016/0005-2760(88)90121-x. [DOI] [PubMed] [Google Scholar]
  23. Croset M., Lagarde M. Enhancement of eicosaenoic acid lipoxygenation in human platelets by 12-hydroperoxy derivative of arachidonic acid. Lipids. 1985 Nov;20(11):743–750. doi: 10.1007/BF02534397. [DOI] [PubMed] [Google Scholar]
  24. Defreyn G., Deckmyn H., Vermylen J. A thromboxane synthetase inhibitor reorients endoperoxide metabolism in whole blood towards prostacyclin and prostaglandin E2. Thromb Res. 1982 Jun 15;26(6):389–400. doi: 10.1016/0049-3848(82)90311-5. [DOI] [PubMed] [Google Scholar]
  25. Drazen J. M., Austen K. F., Lewis R. A., Clark D. A., Goto G., Marfat A., Corey E. J. Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci U S A. 1980 Jul;77(7):4354–4358. doi: 10.1073/pnas.77.7.4354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Dyerberg J. Linolenate-derived polyunsaturated fatty acids and prevention of atherosclerosis. Nutr Rev. 1986 Apr;44(4):125–134. doi: 10.1111/j.1753-4887.1986.tb07603.x. [DOI] [PubMed] [Google Scholar]
  27. Egan R. W., Gale P. H., Baptista E. M., Kennicott K. L., VandenHeuvel W. J., Walker R. W., Fagerness P. E., Kuehl F. A., Jr Oxidation reactions by prostaglandin cyclooxygenase-hydroperoxidase. J Biol Chem. 1981 Jul 25;256(14):7352–7361. [PubMed] [Google Scholar]
  28. Feinmark S. J., Cannon P. J. Endothelial cell leukotriene C4 synthesis results from intercellular transfer of leukotriene A4 synthesized by polymorphonuclear leukocytes. J Biol Chem. 1986 Dec 15;261(35):16466–16472. [PubMed] [Google Scholar]
  29. Feinmark S. J., Cannon P. J. Vascular smooth muscle cell leukotriene C4 synthesis: requirement for transcellular leukotriene A4 metabolism. Biochim Biophys Acta. 1987 Nov 21;922(2):125–135. doi: 10.1016/0005-2760(87)90146-9. [DOI] [PubMed] [Google Scholar]
  30. Feuerstein N., Bash J. A., Woody J. N., Ramwell P. W. Leukotriene C stimulates prostaglandin release from rat peritoneal macrophages. Biochem Biophys Res Commun. 1981 Jun 16;100(3):1085–1090. doi: 10.1016/0006-291x(81)91934-3. [DOI] [PubMed] [Google Scholar]
  31. FitzGerald G. A., Smith B., Pedersen A. K., Brash A. R. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. N Engl J Med. 1984 Apr 26;310(17):1065–1068. doi: 10.1056/NEJM198404263101701. [DOI] [PubMed] [Google Scholar]
  32. Fitzpatrick F. A., Morton D. R., Wynalda M. A. Albumin stabilizes leukotriene A4. J Biol Chem. 1982 May 10;257(9):4680–4683. [PubMed] [Google Scholar]
  33. Fitzpatrick F., Liggett W., McGee J., Bunting S., Morton D., Samuelsson B. Metabolism of leukotriene A4 by human erythrocytes. A novel cellular source of leukotriene B4. J Biol Chem. 1984 Sep 25;259(18):11403–11407. [PubMed] [Google Scholar]
  34. Goetzl E. J., Brash A. R., Tauber A. I., Oates J. A., Hubbard W. C. Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids. Immunology. 1980 Apr;39(4):491–501. [PMC free article] [PubMed] [Google Scholar]
  35. Goldyne M. E., Burrish G. F., Poubelle P., Borgeat P. Arachidonic acid metabolism among human mononuclear leukocytes. Lipoxygenase-related pathways. J Biol Chem. 1984 Jul 25;259(14):8815–8819. [PubMed] [Google Scholar]
  36. Goldyne M. E., Stobo J. D. Human monocytes synthesize eicosanoids from T lymphocyte-derived arachidonic acid. Prostaglandins. 1982 Nov;24(5):623–630. doi: 10.1016/0090-6980(82)90032-6. [DOI] [PubMed] [Google Scholar]
  37. Goodnight S. H., Jr, Harris W. S., Connor W. E., Illingworth D. R. Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. Arteriosclerosis. 1982 Mar-Apr;2(2):87–113. doi: 10.1161/01.atv.2.2.87. [DOI] [PubMed] [Google Scholar]
  38. Gorman R. R., Oglesby T. D., Bundy G. L., Hopkins N. K. Evidence for 15-HETE synthesis by human umbilical vein endothelial cells. Circulation. 1985 Oct;72(4):708–712. doi: 10.1161/01.cir.72.4.708. [DOI] [PubMed] [Google Scholar]
  39. Greenwald S. E., Letts L. G., Newman D. L., Piper P. J. Actions of cysteinyl leukotrienes in coronary, femoral and carotid vessels of the pig. Eur J Pharmacol. 1984 Aug 3;103(1-2):107–114. doi: 10.1016/0014-2999(84)90195-x. [DOI] [PubMed] [Google Scholar]
  40. Guichardant M., Lagarde M. Monohydroxylated fatty acid substrate specificity of human leukocyte 5-lipoxygenase and omega-hydroxylase. Biochem J. 1988 Dec 15;256(3):879–883. doi: 10.1042/bj2560879. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Ham E. A., Egan R. W., Soderman D. D., Gale P. H., Kuehl F. A., Jr Peroxidase-dependent deactivation of prostacyclin synthetase. J Biol Chem. 1979 Apr 10;254(7):2191–2194. [PubMed] [Google Scholar]
  42. Hemler M. E., Graff G., Lands W. E. Accelerative autoactivation of prostaglandin biosynthesis by PGG2. Biochem Biophys Res Commun. 1978 Dec 29;85(4):1325–1331. doi: 10.1016/0006-291x(78)91148-8. [DOI] [PubMed] [Google Scholar]
  43. Humes J. L., Opas E. E., Galavage M., Soderman D., Bonney R. J. Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids. Biochem J. 1986 Jan 1;233(1):199–206. doi: 10.1042/bj2330199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Jakschik B. A., Lee L. H. Enzymatic assembly of slow reacting substance. Nature. 1980 Sep 4;287(5777):51–52. doi: 10.1038/287051a0. [DOI] [PubMed] [Google Scholar]
  45. Kernoff P. B., Willis A. L., Stone K. J., Davies J. A., McNicol G. P. Antithrombotic potential of dihomo-gamma-linolenic acid in man. Br Med J. 1977 Dec 3;2(6100):1441–1444. doi: 10.1136/bmj.2.6100.1441. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Kobayashi T., Levine L. Arachidonic acid metabolism by erythrocytes. J Biol Chem. 1983 Aug 10;258(15):9116–9121. [PubMed] [Google Scholar]
  47. Kuehl F. A., Jr, Egan R. W. Prostaglandins, arachidonic acid, and inflammation. Science. 1980 Nov 28;210(4473):978–984. doi: 10.1126/science.6254151. [DOI] [PubMed] [Google Scholar]
  48. Lagarde M. Metabolism of fatty acids by platelets and the functions of various metabolites in mediating platelet function. Prog Lipid Res. 1988;27(2):135–152. doi: 10.1016/0163-7827(88)90008-2. [DOI] [PubMed] [Google Scholar]
  49. Lands W. E. Biological consequences of fatty acid oxygenase reaction mechanisms. Prostaglandins Leukot Med. 1984 Jan;13(1):35–46. doi: 10.1016/0262-1746(84)90100-8. [DOI] [PubMed] [Google Scholar]
  50. Lapetina E. G., Schmitges C. J., Chandrabose K., Cuatrecases P. Cyclic adenosine 3',5'-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets. Biochem Biophys Res Commun. 1977 Jun 6;76(3):828–835. doi: 10.1016/0006-291x(77)91575-3. [DOI] [PubMed] [Google Scholar]
  51. Lee T. H., Mencia-Huerta J. M., Shih C., Corey E. J., Lewis R. A., Austen K. F. Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils. J Clin Invest. 1984 Dec;74(6):1922–1933. doi: 10.1172/JCI111612. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Lewis R. A., Soter N. A., Diamond P. T., Austen K. F., Oates J. A., Roberts L. J., 2nd Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. J Immunol. 1982 Oct;129(4):1627–1631. [PubMed] [Google Scholar]
  53. Lindgren J. A., Hansson G., Samuelsson B. Formation of novel hydroxylated eicosatetraenoic acids in preparations of human polymorphonuclear leukocytes. FEBS Lett. 1981 Jun 15;128(2):329–335. doi: 10.1016/0014-5793(81)80110-x. [DOI] [PubMed] [Google Scholar]
  54. Liston T. E., Roberts L. J., 2nd Transformation of prostaglandin D2 to 9 alpha, 11 beta-(15S)-trihydroxyprosta-(5Z,13E)-dien-1-oic acid (9 alpha, 11 beta-prostaglandin F2): a unique biologically active prostaglandin produced enzymatically in vivo in humans. Proc Natl Acad Sci U S A. 1985 Sep;82(18):6030–6034. doi: 10.1073/pnas.82.18.6030. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Lorenzet R., Niemetz J., Marcus A. J., Broekman M. J. Enhancement of mononuclear procoagulant activity by platelet 12-hydroxyeicosatetraenoic acid. J Clin Invest. 1986 Aug;78(2):418–423. doi: 10.1172/JCI112592. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. Maclouf J. A., Murphy R. C. Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4. J Biol Chem. 1988 Jan 5;263(1):174–181. [PubMed] [Google Scholar]
  57. Maclouf J., Del Maschio A., Grange M. J., Corvazier E., Borgeat P. Regulation and manipulation of arachidonate cascade in cell-cell interaction. Adv Prostaglandin Thromboxane Leukot Res. 1985;15:209–211. [PubMed] [Google Scholar]
  58. Maclouf J., de Laclos B. F., Borgeat P. Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid. Proc Natl Acad Sci U S A. 1982 Oct;79(19):6042–6046. doi: 10.1073/pnas.79.19.6042. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Malmsten C., Granström E., Samuelsson B. Cyclic AMP inhibits synthesis of prostaglandin endoperoxide (PGG2) in human platelets. Biochem Biophys Res Commun. 1976 Jan 26;68(2):569–576. doi: 10.1016/0006-291x(76)91183-9. [DOI] [PubMed] [Google Scholar]
  60. Marcus A. J., Broekman M. J., Safier L. B., Ullman H. L., Islam N., Sherhan C. N., Rutherford L. E., Korchak H. M., Weissmann G. Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro. Biochem Biophys Res Commun. 1982 Nov 16;109(1):130–137. doi: 10.1016/0006-291x(82)91575-3. [DOI] [PubMed] [Google Scholar]
  61. Marcus A. J., Safier L. B., Ullman H. L., Broekman M. J., Islam N., Oglesby T. D., Gorman R. R. 12S,20-dihydroxyicosatetraenoic acid: a new icosanoid synthesized by neutrophils from 12S-hydroxyicosatetraenoic acid produced by thrombin- or collagen-stimulated platelets. Proc Natl Acad Sci U S A. 1984 Feb;81(3):903–907. doi: 10.1073/pnas.81.3.903. [DOI] [PMC free article] [PubMed] [Google Scholar]
  62. Marcus A. J., Safier L. B., Ullman H. L., Islam N., Broekman M. J., Falck J. R., Fischer S., von Schacky C. Platelet-neutrophil interactions. (12S)-hydroxyeicosatetraen-1,20-dioic acid: a new eicosanoid synthesized by unstimulated neutrophils from (12S)-20-dihydroxyeicosatetraenoic acid. J Biol Chem. 1988 Feb 15;263(5):2223–2229. [PubMed] [Google Scholar]
  63. Marcus A. J., Safier L. B., Ullman H. L., Islam N., Broekman M. J., von Schacky C. Studies on the mechanism of omega-hydroxylation of platelet 12-hydroxyeicosatetraenoic acid (12-HETE) by unstimulated neutrophils. J Clin Invest. 1987 Jan;79(1):179–187. doi: 10.1172/JCI112781. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Marcus A. J., Weksler B. B., Jaffe E. A., Broekman M. J. Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cells. J Clin Invest. 1980 Nov;66(5):979–986. doi: 10.1172/JCI109967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. McGee J. E., Fitzpatrick F. A. Erythrocyte-neutrophil interactions: formation of leukotriene B4 by transcellular biosynthesis. Proc Natl Acad Sci U S A. 1986 Mar;83(5):1349–1353. doi: 10.1073/pnas.83.5.1349. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. McIntyre T. M., Zimmerman G. A., Prescott S. M. Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc Natl Acad Sci U S A. 1986 Apr;83(7):2204–2208. doi: 10.1073/pnas.83.7.2204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Mehta P., Mehta J., Lawson D., Krop I., Letts L. G. Leukotrienes potentiate the effects of epinephrine and thrombin on human platelet aggregation. Thromb Res. 1986 Mar 1;41(5):731–738. doi: 10.1016/0049-3848(86)90370-1. [DOI] [PubMed] [Google Scholar]
  68. Milks M. M., Sprecher H. Metabolism of 4,7,10,13,16-docosapentaenoic acid by human platelet cyclooxygenase and lipoxygenase. Biochim Biophys Acta. 1985 Jun 14;835(1):29–35. doi: 10.1016/0005-2760(85)90026-8. [DOI] [PubMed] [Google Scholar]
  69. Miller D. K., Sadowski S., Soderman D. D., Kuehl F. A., Jr Endothelial cell prostacyclin production induced by activated neutrophils. J Biol Chem. 1985 Jan 25;260(2):1006–1014. [PubMed] [Google Scholar]
  70. Mills D. C., Macfarlane D. E. Stimulation of human platelet adenylate cyclase by prostaglandin D2. Thromb Res. 1974 Sep;5(3):401–412. doi: 10.1016/0049-3848(74)90176-5. [DOI] [PubMed] [Google Scholar]
  71. Minkes M., Stanford N., Chi M. M., Roth G. J., Raz A., Needleman P., Majerus P. W. Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions. J Clin Invest. 1977 Mar;59(3):449–454. doi: 10.1172/JCI108659. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. Moncada S. Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin. Br J Pharmacol. 1982 May;76(1):3–31. doi: 10.1111/j.1476-5381.1982.tb09186.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Morita I., Takahashi R., Saito Y., Murota S. Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. J Biol Chem. 1983 Sep 10;258(17):10197–10199. [PubMed] [Google Scholar]
  74. Nagaoka I., Yamashita T. Conversion of leukotriene C4 to leukotriene D4 by a cell-surface enzyme of rat macrophages. Biochem Biophys Res Commun. 1987 Aug 31;147(1):282–287. doi: 10.1016/s0006-291x(87)80118-3. [DOI] [PubMed] [Google Scholar]
  75. Nakao J., Ooyama T., Chang W. C., Murota S., Orimo H. Platelets stimulate aortic smooth muscle cell migration in vitro. Involvement of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid. Atherosclerosis. 1982 Jun;43(2-3):143–150. doi: 10.1016/0021-9150(82)90018-1. [DOI] [PubMed] [Google Scholar]
  76. Needleman P., Minkes M., Raz A. Thromboxanes: selective biosynthesis and distinct biological properties. Science. 1976 Jul 9;193(4248):163–165. doi: 10.1126/science.945611. [DOI] [PubMed] [Google Scholar]
  77. Needleman P., Raz A., Minkes M. S., Ferrendelli J. A., Sprecher H. Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties. Proc Natl Acad Sci U S A. 1979 Feb;76(2):944–948. doi: 10.1073/pnas.76.2.944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Needleman P., Turk J., Jakschik B. A., Morrison A. R., Lefkowith J. B. Arachidonic acid metabolism. Annu Rev Biochem. 1986;55:69–102. doi: 10.1146/annurev.bi.55.070186.000441. [DOI] [PubMed] [Google Scholar]
  79. Pace-Asciak C. R. Arachidonic acid epoxides. Demonstration through [18O]oxygen studies of an intramolecular transfer of the terminal hydroxyl group of (12S)-hydroperoxyeicosa-5,8,10,14-tetraenoic acid to form hydroxyepoxides. J Biol Chem. 1984 Jul 10;259(13):8332–8337. [PubMed] [Google Scholar]
  80. Pace-Asciak C. R. Hemoglobin- and hemin-catalyzed transformation of 12L-hydroperoxy-5,8,10,14-eicosatetraenoic acid. Biochim Biophys Acta. 1984 May 11;793(3):485–488. doi: 10.1016/0005-2760(84)90267-4. [DOI] [PubMed] [Google Scholar]
  81. Papp A. C., Crowe L., Pettigrew L. C., Wu K. K. Production of eicosanoids by deendothelialized rabbit aorta: interaction between platelets and vascular wall in the synthesis of prostacyclin. Thromb Res. 1986 May 15;42(4):549–556. doi: 10.1016/0049-3848(86)90218-5. [DOI] [PubMed] [Google Scholar]
  82. Piper P. J., Galton S. A. Generation of leukotriene B4 and leukotriene E4 from porcine pulmonary artery. Prostaglandins. 1984 Dec;28(6):905–914. doi: 10.1016/0090-6980(84)90043-1. [DOI] [PubMed] [Google Scholar]
  83. Ramesha C. S., Pickett W. C. Platelet-activating factor and leukotriene biosynthesis is inhibited in polymorphonuclear leukocytes depleted of arachidonic acid. J Biol Chem. 1986 Jun 15;261(17):7592–7595. [PubMed] [Google Scholar]
  84. Reingold D. F., Kawasaki A., Needleman P. A novel prostaglandin 11-keto reductase found in rabbit liver. Biochim Biophys Acta. 1981 May 14;659(1):179–188. doi: 10.1016/0005-2744(81)90282-5. [DOI] [PubMed] [Google Scholar]
  85. Rådmark O., Shimizu T., Fitzpatrick F., Samuelsson B. Hemoprotein catalysis of leukotriene formation. Biochim Biophys Acta. 1984 Mar 7;792(3):324–329. doi: 10.1016/0005-2760(84)90200-5. [DOI] [PubMed] [Google Scholar]
  86. Salzman E. W., Kensler P. C., Levine L. Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function. Ann N Y Acad Sci. 1972 Oct 27;201:61–71. doi: 10.1111/j.1749-6632.1972.tb16287.x. [DOI] [PubMed] [Google Scholar]
  87. Samuelsson B., Goldyne M., Granström E., Hamberg M., Hammarström S., Malmsten C. Prostaglandins and thromboxanes. Annu Rev Biochem. 1978;47:997–1029. doi: 10.1146/annurev.bi.47.070178.005025. [DOI] [PubMed] [Google Scholar]
  88. Schafer A. I., Cooper B., O'Hara D., Handin R. I. Identification of platelet receptors for prostaglandin I2 and D2. J Biol Chem. 1979 Apr 25;254(8):2914–2917. [PubMed] [Google Scholar]
  89. Schafer A. I., Crawford D. D., Gimbrone M. A., Jr Unidirectional transfer of prostaglandin endoperoxides between platelets and endothelial cells. J Clin Invest. 1984 Apr;73(4):1105–1112. doi: 10.1172/JCI111296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. Schrier S. L. Human erythrocyte membrane enzymes: current status and clinical correlates. Blood. 1977 Aug;50(2):227–237. [PubMed] [Google Scholar]
  91. Serhan C. N., Hamberg M., Samuelsson B. Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. Biochem Biophys Res Commun. 1984 Feb 14;118(3):943–949. doi: 10.1016/0006-291x(84)91486-4. [DOI] [PubMed] [Google Scholar]
  92. Setty B. N., Berger M., Stuart M. J. 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. Biochem Biophys Res Commun. 1987 Jul 31;146(2):502–509. doi: 10.1016/0006-291x(87)90557-2. [DOI] [PubMed] [Google Scholar]
  93. Siegel M. I., McConnell R. T., Abrahams S. L., Porter N. A., Cuatrecasas P. Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase. Biochem Biophys Res Commun. 1979 Aug 28;89(4):1273–1280. doi: 10.1016/0006-291x(79)92146-6. [DOI] [PubMed] [Google Scholar]
  94. Siegel M. I., McConnell R. T., Bonser R. W., Cuatrecasas P. The lipoxygenase product, 5-hydroperoxy-arachidonic acid, augments chemotactic peptide-stimulated arachidonic acid release from HL60 granulocytes. Biochem Biophys Res Commun. 1982 Feb 11;104(3):874–881. doi: 10.1016/0006-291x(82)91330-4. [DOI] [PubMed] [Google Scholar]
  95. Siegel M. I., McConnell R. T., Cuatrecasas P. Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway. Proc Natl Acad Sci U S A. 1979 Aug;76(8):3774–3778. doi: 10.1073/pnas.76.8.3774. [DOI] [PMC free article] [PubMed] [Google Scholar]
  96. Snyder G. D., Capdevila J., Chacos N., Manna S., Falck J. R. Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites. Proc Natl Acad Sci U S A. 1983 Jun;80(11):3504–3507. doi: 10.1073/pnas.80.11.3504. [DOI] [PMC free article] [PubMed] [Google Scholar]
  97. Soberman R. J., Harper T. W., Betteridge D., Lewis R. A., Austen K. F. Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. J Biol Chem. 1985 Apr 10;260(7):4508–4515. [PubMed] [Google Scholar]
  98. Turner S. R., Tainer J. A., Lynn W. S. Biogenesis of chemotactic molecules by the arachidonate lipoxygenase system of platelets. Nature. 1975 Oct 23;257(5528):680–681. doi: 10.1038/257680a0. [DOI] [PubMed] [Google Scholar]
  99. VanRollins M., Horrocks L., Sprecher H. Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. Biochim Biophys Acta. 1985 Feb 8;833(2):272–280. doi: 10.1016/0005-2760(85)90199-7. [DOI] [PubMed] [Google Scholar]
  100. Vanderhoek J. Y., Bryant R. W., Bailey J. M. 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. J Biol Chem. 1980 Jul 10;255(13):5996–5998. [PubMed] [Google Scholar]
  101. Vanderhoek J. Y., Bryant R. W., Bailey J. M. Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid. J Biol Chem. 1980 Nov 10;255(21):10064–10066. [PubMed] [Google Scholar]
  102. Vanderhoek J. Y., Tare N. S., Bailey J. M., Goldstein A. L., Pluznik D. H. New role for 15-hydroxyeicosatetraenoic acid. Activator of leukotriene biosynthesis in PT-18 mast/basophil cells. J Biol Chem. 1982 Oct 25;257(20):12191–12195. [PubMed] [Google Scholar]
  103. Vatassery G. T. In vitro oxidation of alpha-tocopherol (vitamin E) in human platelets upon incubation with unsaturated fatty acids, diamide and superoxide. Biochim Biophys Acta. 1987 Nov 6;926(2):160–169. doi: 10.1016/0304-4165(87)90233-9. [DOI] [PubMed] [Google Scholar]
  104. Vatassery G. T., Johnson G. J., Krezowski A. M. Changes in vitamin E concentrations in human plasma and platelets with age. J Am Coll Nutr. 1983;2(4):369–375. doi: 10.1080/07315724.1983.10719934. [DOI] [PubMed] [Google Scholar]
  105. Vericel E., Croset M., Sedivy P., Courpron P., Dechavanne M., Lagarde M. Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. Thromb Res. 1988 Feb 1;49(3):331–342. doi: 10.1016/0049-3848(88)90313-1. [DOI] [PubMed] [Google Scholar]
  106. Watanabe J., Umeda F., Wakasugi H., Ibayashi H. Effect of vitamin E on platelet aggregation in diabetes mellitus. Thromb Haemost. 1984 Jul 29;51(3):313–316. [PubMed] [Google Scholar]
  107. Willis A. L. Nutritional and pharmacological factors in eicosanoid biology. Nutr Rev. 1981 Aug;39(8):289–301. doi: 10.1111/j.1753-4887.1981.tb06794.x. [DOI] [PubMed] [Google Scholar]
  108. Wong P. Y., Lee W. H., Chao P. H., Reiss R. F., McGiff J. C. Metabolism of prostacyclin by 9-hydroxyprostaglandin dehydrogenase in human platelets. Formation of a potent inhibitor of platelet aggregation and enzyme purification. J Biol Chem. 1980 Oct 10;255(19):9021–9024. [PubMed] [Google Scholar]
  109. Wong P. Y., Malik K. U., Desiderio D. M., McGiff J. C., Sun F. F. Hepatic metabolism of prostacyclin (PGI2) in the rabbit: formation of a potent novel inhibitor of platelet aggregation. Biochem Biophys Res Commun. 1980 Mar 28;93(2):486–494. doi: 10.1016/0006-291x(80)91103-1. [DOI] [PubMed] [Google Scholar]
  110. Wong P. Y. Purification and partial characterization of prostaglandin D2 11-keto reductase in rabbit liver. Biochim Biophys Acta. 1981 May 14;659(1):169–178. doi: 10.1016/0005-2744(81)90281-3. [DOI] [PubMed] [Google Scholar]
  111. Wu K. K., Papp A. C., Manner C. E., Hall E. R. Interaction between lymphocytes and platelets in the synthesis of prostacyclin. J Clin Invest. 1987 Jun;79(6):1601–1606. doi: 10.1172/JCI112995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  112. Yamaja Setty B. N., Berger M., Stuart M. J. 13-Hydroxyoctadeca-9,11-dienoic acid (13-HODE) inhibits thromboxane A2 synthesis, and stimulates 12-HETE production in human platelets. Biochem Biophys Res Commun. 1987 Oct 29;148(2):528–533. doi: 10.1016/0006-291x(87)90908-9. [DOI] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES