Table 1.
Characteristics of GBS prophages.
| Prophage | Cluster | Genome Size (bp) | % GC | No. of Genes | Type of Integrase | Gene Upstream of Insertion Site (Att Site) | Inserts Into | Gene Downstream of Insertion Site (Att Site) | Attachment Site |
|---|---|---|---|---|---|---|---|---|---|
| Javan 5 (2603 V/R) | A | 40,574 | 35.3 | 78 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| Javan 7 (A909) | A | 37,225 | 37.1 | 62 | Tyrosine | hypothetical protein | N/A | HU family DNA-binding protein | TTATAGTTGGGGCGAATTTGGGGCATAA |
| prophigbs515 | A | 40,634 | 34.9 | 89 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC2-1 | A | 39,700 | 36.8 | 66 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC5 | A | 46,132 | 35.9 | 80 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC15 | A | 38,551 | 36.7 | 68 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC16 | A | 43,746 | 36.4 | 71 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC21-2 | A | 43,397 | 36.6 | 73 | Serine | N-acetylmannosamine kinase | acetyl xylan esterase | Sialic acid utilization regulator, RpiR family | GATTTTGATGACTTC |
| prophiDMC25 | A | 38,551 | 36.7 | 68 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC33-1 | A | 43,746 | 36.4 | 72 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC34 | A | 37,294 | 36.7 | 62 | Serine | ComGF | N/A | ComGB | TAAATTTTTC |
| prophiDMC43-1 | A | 43,738 | 38.6 | 58 | Tyrosine | bacterial ribosome SSU maturation protein RimP | tRNA-Ser-GGA | tRNA (guanine(46)-N(7))-methyltransferase | AATCCCCTCCTCTCCTTT |
| prophiDMC47 | A | 45,805 | 35.8 | 81 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC48 | A | 45,885 | 35.8 | 80 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC49 | A | 45,685 | 35.8 | 84 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC51 | A | 45,805 | 35.8 | 82 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC61 | A | 45,686 | 35.8 | 80 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC64 | A | 40,022 | 37 | 68 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC66-1 | A | 45,884 | 35.8 | 80 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC67 | A | 37,262 | 36.8 | 61 | Serine | ComGF | N/A | ComGB | TAAATTTTTC |
| prophiDMC68-1 | A | 45,777 | 35.8 | 80 | Tyrosine | integrase | tRNA-Arg | LSU ribosomal protein L19p | ATGTCCCCTGCC |
| prophiDMC6 | B | 36,849 | 39.7 | 57 | Serine | ComGD | ComGC | ComGB | TAAATTTTTC |
| prophiDMC17 | B | 36,582 | 39.7 | 54 | Serine | ComGD | ComGC | ComGB | TAAATTTTTC |
| prophiDMC30 | B | 36,585 | 39.7 | 56 | Serine | ComGD | ComGC | ComGB | TAAATTTTTC |
| prophiDMC36 | B | 36,581 | 39.6 | 54 | Serine | ComGD | ComGC | ComGB | TAAATTTTTC |
| prophiDMC62 | B | 36,534 | 39.7 | 54 | Serine | ComGD | ComGC | ComGB | TAAATTTTTC |
| prophiCNCTC 10/84 | C | 40,696 | 36.4 | 67 | Tyrosine | hypothetical protein | N/A | HU family DNA-binding protein | TTATAGTTGGGGCGAATTTGGGGCATAA |
| prophiDMC4 | C | 38,991 | 36.2 | 55 | Tyrosine | hypothetical protein | N/A | DNA binding protein HbSu | TTATGCCCCAAATTCGCCCCAACTATAA |
| prophiDMC9 | C | 38,963 | 36.2 | 55 | Tyrosine | hypothetical protein | N/A | DNA-binding protein HbSu | TTATGCCCCAAATTCGCCCCAACTATAA |
| prophiDMC69 | C | 38,991 | 36.2 | 65 | Tyrosine | hypothetical protein | N/A | DNA binding protein HbSu | TTATAGTTGGGGCGAATTTGGGGCATAA |
| Javan 8 (A909) | D | 45,841 | 42.2 | 43 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiCJBIII (CJBIII) | D | 48,336 | 41.8 | 46 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC1 | D | 45,705 | 42.5 | 45 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC2-2 | D | 46,693 | 42.5 | 49 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC21-1 | D | 45,421 | 42.5 | 45 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC24 | D | 43,168 | 43.9 | 46 | Serine | hypothetical protein | N/A | hydrolase (HAD superfamily) | TGGTATAAT |
| prophiDMC28 | D | 45,702 | 42.5 | 45 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC33-2 | D | 46,690 | 42.5 | 45 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC43-2 | D | 44,915 | 42.8 | 44 | Serine | transcriptional regulator AcrR family | N/A | hypothetical protein | ACTTTTGAAAAGGAGA |
| prophiDMC66-2 | D | 43,168 | 43.9 | 47 | Serine | hypothetical protein | N/A | hydrolase (HAD superfamily) | TGGTATAAT |
| Javan 6 (2603 V/R) | E | 34,100 | 40.2 | 40 | Tyrosine | alkyl hydroperoxide reductase protein F | tRNA-Cys | Na+/H+ antiporter | AATCCGTCTACCGCCT |
| prophiDMC20 | E | 36,343 | 40 | 53 | Tyrosine | alkyl hydroperoxide reductase protein F | tRNA-Cys | Na+/H+ antiporter | AATCCGTCTACCGCCT |
| prophiDMC27 | E | 36,093 | 40 | 53 | Tyrosine | alkyl hydroperoxide reductase protein F | tRNA-Cys | Na+/H+ antiporter | AATCCGTCTACCGCCT |