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. 1995 Aug 15;310(Pt 1):95–99. doi: 10.1042/bj3100095

A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media.

M T Webster 1, N Groome 1, P T Francis 1, B R Pearce 1, F E Sherriff 1, G Thinakaran 1, K M Felsenstein 1, W Wasco 1, R E Tanzi 1, D M Bowen 1
PMCID: PMC1135859  PMID: 7646477

Abstract

A monoclonal antibody, 3B11, was raised to a novel protein, amyloid precursor-like protein 2, which did not recognize amyloid precursor protein. Multiple bands were detected in human brain fractions and cell lysate by Western blotting, indicating the presence of isoforms, 3B11 immunoreactivity was also detected in cerebrospinal fluid and conditioned medium, indicating that the protein is secreted. Immunocytochemistry revealed 3B11 immunoreactivity in sections of human brain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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