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. 1995 Feb 1;305(Pt 3):1027–1030. doi: 10.1042/bj3051027

The expression of interstitial collagenase in human endometrium is controlled by progesterone and by oestradiol and is related to menstruation.

E Marbaix 1, I Kokorine 1, P Henriet 1, J Donnez 1, P J Courtoy 1, Y Eeckhout 1
PMCID: PMC1136361  PMID: 7848264

Abstract

Human endometrial tissue, sampled at different periods of the reproductive cycle, expressed interstitial collagenase mRNA, protein and activity only just before and during the menstrual period. This clear-cut correlation and the inhibition of collagenase expression by progesterone and oestradiol in tissue culture point to a pivotal role of this proteinase in the mechanism of menstrual tissue breakdown and bleeding.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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