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. 1995 Apr 15;307(Pt 2):327–330. doi: 10.1042/bj3070327

Translation in vivo of 5' untranslated-region splice variants of human surfactant protein-A.

A M Karinch 1, J Floros 1
PMCID: PMC1136651  PMID: 7733864

Abstract

Transcripts of human SP-A genes, SP-A1 and SP-A2, undergo alternative splicing of 5' untranslated-region exons. We reverse-transcribed and amplified free cytoplasmic and polysome-bound RNA and showed that (a) all splice variants of both genes are translated in vivo, (b) the relative translatability of splice variants can differ among individuals, and (c) the relative levels of different SP-A splice variants differ among individuals.

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Selected References

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