Genes & Development 19: 570–582 (2005)
In the above-mentioned article, we were alerted to an error in Figures 2C and 7E in which the same microscopy photograph of cultured HeLa cells that had been transfected with an siRNA to knock down expression of HSP70-2 is shown. The images in question were labeled “A2.1” in Figure 2C (top right panel) and “A2.2” in Figure 7E (middle panel), indicating that the two cell samples were transfected with different siRNA candidates; namely, siRNA A2.1 and A2.2, respectively. However, upon reviewing our original data, we determined that the panel in Figure 2C had been mislabeled and should be labeled “A2.2” instead of “A2.1.”
During the course of our study, we expanded the repertoire of siRNAs that were used to knock down each target gene, which led us to change our system of siRNA nomenclature and inadvertently led to the mislabeling error described above. We have included a corrected Figure 2C below and attest that, since siRNA A2.1 and A2.2 reduced levels of HSP70-2 and drove the associated phenotypes to a similar degree, the mislabeling error does not change the conclusions of the article.
doi:10.1101/gad.352065.124