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. 1994 Jul 15;301(Pt 2):317–319. doi: 10.1042/bj3010317

Leishmanial glycosomes contain superoxide dismutase.

R Dey 1, S C Datta 1
PMCID: PMC1137081  PMID: 8042972

Abstract

In this work we report that superoxide dismutase is entrapped in a microbody-like organelle, the glycosome, present in Leishmania spp. Studies on the sensitivity of the enzyme to various inhibitors indicated that glycosomal superoxide dismutase is predominantly of the Cu/Zu type. Localization of superoxide dismutase in glycosomes points to the major importance of this organelle in the survival of this pathogen, suggesting a new approach towards chemotherapy for leishmaniasis.

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Selected References

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