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. 2024 Sep 8;16(1):2400414. doi: 10.1080/19420862.2024.2400414

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© 2024 Boehringer Ingelheim. Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 5. — Correlations of the mAb screening by MR-AC. The elution peak area was correlated with the respective symmetrical high-mannose glyco-pair percentage (a). The asymmetry at the flow-through peak height of 30% was correlated with the respective asymmetrical high-mannose glyco-pair percentage (b). The percentage of the symmetrical or asymmetrical high-mannose glycol-pair of each mAb was determined by RPC-MS after Endo F3 digestion.