Skip to main content
Biochemical Journal logoLink to Biochemical Journal
. 1989 May 15;260(1):295–296. doi: 10.1042/bj2600295

Synthesis of 2-aminoethylarsonic acid. A new synthesis of primary.

K F Geoghegan 1, H B Dixon 1
PMCID: PMC1138661  PMID: 2775191

Abstract

2-Aminoethylarsonic acid was prepared from 2-choloethylarsonic acid. The route constitutes a new procedure for making primary amines from haloalkanes; chloride was displaced by treatment with 2-aminoethanol at 70 degrees C, and the product was converted into the required primary amine by treatment with periodate.

Full text

PDF
295

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams S. R., Sparkes M. J., Dixon H. B. The arsonomethyl analogue of 3-phosphoglycerate. Biochem J. 1983 Jul 1;213(1):211–215. doi: 10.1042/bj2130211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fields R., Dixon H. B. A spectrophotometric method for the microdetermination of periodate. Biochem J. 1968 Aug;108(5):883–887. doi: 10.1042/bj1080883. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Geoghegan K. F., Ybarra D. M., Feeney R. E. Reversible reductive alkylation of amino groups in proteins. Biochemistry. 1979 Nov 27;18(24):5392–5399. doi: 10.1021/bi00591a021. [DOI] [PubMed] [Google Scholar]
  4. Sparkes M. J., Dixon H. B., Geoghegan K. F., Visedo-Gonzalez E. Application of the synthetic method to other amines. Biochem J. 1989 May 15;260(1):296–297. doi: 10.1042/bj2600296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Tamari M., Maget-Dana R., Marmouyet J., Douste-Blazy L. CMP-aminoéthylphosphonate: intermédiaire de la biosynthèse des phosphonolipides dans de foie de rat. Biochimie. 1973;55(10):1311–1312. [PubMed] [Google Scholar]
  6. Visedo-Gonzalez E., Dixon H. B. 2-Aminoethylarsonic acid as an analogue of ethanolamine phosphate. Endowment of ethanolamine-phosphate cytidylyltransferase with CTP pyrophosphatase activity. Biochem J. 1989 May 15;260(1):299–301. doi: 10.1042/bj2600299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. WADE H. E., MORGAN D. M. Detection of phosphate esters on paper chromatograms. Nature. 1953 Mar 21;171(4351):529–530. doi: 10.1038/171529a0. [DOI] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES