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. 1989 Jun 1;260(2):601–604. doi: 10.1042/bj2600601

The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region.

M Leyh-Bouille 1, J Van Beeumen 1, S Renier-Pirlot 1, B Joris 1, M Nguyen-Distèche 1, J M Ghuysen 1
PMCID: PMC1138712  PMID: 2764892

Abstract

The N-terminal region of the Streptomyces K15 DD-peptidase/penicillin-binding protein shows high homology with that of other penicillin-interactive proteins or domains. The active-site serine residue of the conserved tetrad Ser-Xaa-Xaa-Lys occurs at position 35. There is no indication for the presence of a signal peptide or an N-terminal hydrophobic sequence, suggesting that the Streptomyces K15 enzyme is probably anchored to the membrane by a C-terminal peptide segment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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