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. 1989 Jul 1;261(1):57–61. doi: 10.1042/bj2610057

Interferon alters the pattern of secreted proteins from Ehrlich ascites-tumour cells.

S Tominaga 1, K Tominaga 1
PMCID: PMC1138780  PMID: 2775220

Abstract

Treatment of Ehrlich ascites-tumour (EAT) cells with interferon (IFN) abolished their ability to secrete a 32 kDa protein that was secreted by growing EAT cells. These IFN-treated cells secreted two proteins (molecular masses 100 and 89 kDa as estimated by SDS/polyacrylamide-gel electrophoresis) that were not detected in two-dimensional gel electrophoresis of the culture fluid of untreated EAT cells. The sequence of 20 amino acids from the N-terminal end of the 32 kDa protein was very similar to portions of sequences of mouse proviral gag proteins.

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Selected References

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