Figure 5.

Differential gene expression in MLO-Y4 cells following Pls3 knockdown. (A) Expression of Pls3 analyzed by RNA sequencing. Significant effect of the treatment: ** p < 0.01. (B) The expression of actin-binding proteins was analyzed by RNA sequencing. (C) Heat map shows the expression pattern of mRNAs between the si-Con and si-Pls3 groups: differentially upregulated mRNAs (total 259), and differentially downregulated mRNAs (total 368). (D) KEGG pathway enrichment analysis based on mRNA expression differences between the si-Con and si-Pls3 groups.