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Journal of Translational Medicine logoLink to Journal of Translational Medicine
. 2024 Sep 13;22:842. doi: 10.1186/s12967-024-05632-7

Correction to: Lenvatinib inhibits the growth of gastric cancer patient‑derived xenografts generated from a heterogeneous populations

John D Karalis 1,2,#, Lynn Y Yoon 1,2,#, Suntrea T G Hammer 3, Changjin Hong 4, Min Zhu 2, Ibrahim Nassour 5, Michelle R Ju 1, Shu Xiao 2, Esther C Castro‑Dubon 1,2, Deepak Agrawal 6, Jorge Suarez 7, Scott I Reznik 8, John C Mansour 1, Patricio M Polanco 1, Adam C Yopp 1, Herbert J Zeh III 1, Tae Hyun Hwang 4, Hao Zhu 2, Matthew R Porembka 1,#, Sam C Wang 1,2,9,✉,#
PMCID: PMC11396437  PMID: 39272170

Following publication of the original article [1], we have been notified that Figure 6c was published incorrectly.

It is now:

Fig. 6.

Fig. 6

Lenvatinib treatment reduced blood vessel density and increased apoptosis in PDX tumors. A H&E and CD31 IHC of vehicle and lenvatinib-treated PDXs (200× magnification) B Intratumoral vascular density quantification. Each dot represents one tumor. The error bar represents the standard error of the mean. C Ki-67 staining of vehicle and lenvatinib-treated tumors. D Ki-67 quantification of vehicle and lenvatinib-treated tumors. Each dot represents the average Ki-67% per PDX line. The error bar represents the standard error of the mean. E TUNEL immunofluorescence staining of vehicle and lenvatinib-treated tumors. F Quantification of TUNEL-positive cells. Each dot represents the average TUNEL-positive cells per PDX line. The error bar represents the standard error of the mean

It should be:

Fig. 6.

Fig. 6

Lenvatinib treatment reduced blood vessel density and increased apoptosis in PDX tumors. A H&E and CD31 IHC of vehicle and lenvatinib-treated PDXs (200× magnification) B Intratumoral vascular density quantification. Each dot represents one tumor. The error bar represents the standard error of the mean. C Ki-67 staining of vehicle and lenvatinib-treated tumors. D Ki-67 quantification of vehicle and lenvatinib-treated tumors. Each dot represents the average Ki-67% per PDX line. The error bar represents the standard error of the mean. E TUNEL immunofluorescence staining of vehicle and lenvatinib-treated tumors. F Quantification of TUNEL-positive cells. Each dot represents the average TUNEL-positive cells per PDX line. The error bar represents the standard error of the mean

The original article was updated.

Footnotes

The online version of the original article can be found at 10.1186/s12967-022-03317-7.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

John D. Karalis and Lynn Y. Yoon contributed equally as primary authors.

Matthew R. Porembka and Sam C. Wang contributed equally as co-corresponding authors.

References

  • 1.Karalis et al. Lenvatinib inhibits the growth of gastric cancer patient–derived xenografts generated from a heterogeneous population. (2022);20:116. 10.1186/s12967-022-03317-7 [DOI] [PMC free article] [PubMed]

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