Table 1.
Participants’ general characteristics and the selected biochemical parameters in healthy subjects (Group I, Controls) and patients with functional constipation (Group II).
| Feature | Group I (n = 40) | Group II (n = 40) | p-Value |
|---|---|---|---|
| Age (years) | 37.7 ± 5.8 | 38.0 ± 5.3 | 0.916 |
| Gender—F | 40 | 40 | n/a |
| BMI (kg/m2) | 23.1 ± 0.8 | 23.4 ± 0.5 | 0.054 |
| GFR (mL/min) | 99.3 ± 3.4 | 97.7 ± 4.3 | 0.062 |
| ALT (µ/L) | 16.6 ± 3.8 | 15.3 ± 3.9 | 0.057 |
| AST (µ/L) | 14.7 ± 1.9 | 16.4 ± 1.4 | 0.092 |
| CRP (mg/L) | 3.0 ± 0.8 | 3.1 ± 0.7 | 0.192 |
| FC (µg/g) | 28.3 ± 4.7 | 34.6 ± 7.5 | 0.0007 |
BMI—body mass index, GFR—glomerular filtration rate, ALT—alanine aminotransferase, AST—aspartate aminotransferase, CRP—C-reactive protein, FC—fecal calprotectin; data are presented as average ± SD; differences between groups were assessed by Student’s t-test; n/a not applicable