AUROC of model performance for images captured on high- versus low-cost image acquisition and computational hardware. AUROC compares tile-level accuracy between high-cost Aperio AT2 and low-cost OpenFlexure image acquisition hardware. Model accuracy in terms of AUROC was maintained when the low-cost OpenFlexure device was used for image capture instead of the gold standard Aperio AT2 slide scanner, with chi-squared tests showing no statistically significant differences in model performance between low- and high-cost methods for any of the cancer subtypes (Lung cancer: X2 (1, Nlow-cost = 595, Nhigh-cost = 29532) = 0.363, p = 0.5468; Breast cancer: X2 (1, Nlow-cost = 360, Nhigh-cost = 1947) = 0.286, p = 0.5929; HNSCC: X2 (1, Nlow-cost = 587, Nhigh-cost = 5932) = 0.629, p = 0.4276).