Table 1.

Patient characteristics according to high risk or non high risk status (OlympiA study criteria) among ER-negative (triple negative) early breast cancer.

Characteristic	High risk (N = 211)		Non high risk (N = 169)		p value
	N	%	N	%
Age at diagnosis					0.0558
Mean (SD)	61.2 (16.6)		57.5 (13.7)
Median (Min – Max)	59.6 (25.8–101)		58.9 (27.7–86.4)
Menopausal status at diagnosis					0.7948
Menopaused	126	63.3	58	35.4
Pre-menopaused	73	36.7	106	64.6
Unknown	12		5
Germline BRCA mutation					0.547
BRCA1	9	20.0	12	26.7
BRCA2	3	6.7	1	2.2
Undetected	33	73.3	32	71.1
Unknown/not performed	166		124
Axillary lymph node status (clinical)					<0.0001
Negative	119	56.7	144	85.7
Positive	91	43.3	24	14.3
Unknown	1		1
Clinical stage (cAJCC)					<0.0001a
0	1	0.5	0	0
IA	47	22.5	120	72.3
IIA	75	35.9	26	15.7
IIB	50	23.9	11	6.6
IIIA	15	7.2	2	1.2
IIIB	16	7.7	6	3.6
IIIC	5	2.4	1	0.6
Unknown	2		3
Pathological stage (pAJCC)					<0.0001
0	0	0	32	19.2
IA	15	7.3	134	80.2
IIA	114	55.3	0	0
IIB	36	17.5	0	0
IIIA	23	11.2	0	0
IIIB	5	2.4	1	0.6
IIIC	13	6.3	0	0
Unknown	5		2
Histological subtype					0.4049
Ductal	192	91.4	152	89.9
Lobular	9	4.3	5	3.0
Other	9	4.3	12	7.1
Unknown	1		0
HER2 low status					0.4064
0	135	64.0	115	68.0
Low (1+ ou 2+ without FISH amplification	76	36.0	54	32.0
Tumor grade (SBR)					0.0416
I	5	2.4	12	7.3
II	52	25.3	48	29.3
III	149	72.3	104	63.4
Unknown	5		5
Type of breast surgery					<0.0001
Tumorectomy	108	51.2	138	81.7
Mastectomy	103	48.8	31	18.3
Type of axillary surgery					<0.0001
Axillary lymph node dissection	150	73.5	55	32.9
Sentinel lymph node dissection	29	14.2	109	65.3
Both	25	12.3	3	1.8
Unknown	7		2

SD: standard deviation, AJCC: American Joint Committee on Cancer.

^aFisher's exact test.