Abstract
Plasma ultrafiltrable (MgUF) and total magnesium concentrations were measured in 60 insulin dependent diabetics and compared with values in an age matched control group. Although the diabetic patients had lower plasma albumin concentrations (p less than 0.05), both ultrafiltrable and total magnesium concentrations were significantly decreased by 6.8% and 7.6%, respectively, compared with those of the controls (p less than 0.001). In the diabetic group MgUF varied inversely with fasting plasma glucose (r = -0.269, p less than 0.05). In 14 patients with significant hypomagnesaemia, fasting plasma glucose concentration was higher (p less than 0.01) and the diabetes was of shorter duration (p less than 0.05) than in 46 patients with an MgUF in the control range. The fasting urinary magnesium creatinine ratio was greater in the diabetic patients (p less than 0.05). Patients with retinopathy did not have lower plasma magnesium values than those without retinopathy.
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Selected References
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- Canagaratna M. C. Serum magnesium levels in diabetes mellitus. Ceylon Med J. 1984 Jun;29(2):109–111. [PubMed] [Google Scholar]
- Ewald U., Gebre-Medhin M., Tuvemo T. Hypomagnesemia in diabetic children. Acta Paediatr Scand. 1983 May;72(3):367–371. doi: 10.1111/j.1651-2227.1983.tb09730.x. [DOI] [PubMed] [Google Scholar]
- Fujii S., Takemura T., Wada M., Akai T., Okuda K. Magnesium levels of plasma, erythrocyte and urine in patients with diabetes mellitus. Horm Metab Res. 1982 Mar;14(3):161–162. doi: 10.1055/s-2007-1018954. [DOI] [PubMed] [Google Scholar]
- Kroll M. H., Elin R. J. Relationships between magnesium and protein concentrations in serum. Clin Chem. 1985 Feb;31(2):244–246. [PubMed] [Google Scholar]
- Lemann J., Jr, Lennon E. J., Piering W. R., Prien E. L., Jr, Ricanati E. S. Evidence that glucose ingestion inhibits net renal tubular reabsorption of calcium and magnesium in man. J Lab Clin Med. 1970 Apr;75(4):578–585. [PubMed] [Google Scholar]
- Levin G. E., Mather H. M., Pilkington T. R. Tissue magnesium status in diabetes mellitus. Diabetologia. 1981 Aug;21(2):131–134. doi: 10.1007/BF00251280. [DOI] [PubMed] [Google Scholar]
- Mather H. M., Levin G. E. Magnesium status in diabetes. Lancet. 1979 Apr 28;1(8122):924–924. doi: 10.1016/s0140-6736(79)91400-4. [DOI] [PubMed] [Google Scholar]
- Mather H. M., Levin G. E., Nisbet J. A., Hadley L. A., Oakley N. W., Pilkington T. R. Diurnal profiles of plasma magnesium and blood glucose in diabetes. Diabetologia. 1982 Mar;22(3):180–183. doi: 10.1007/BF00283749. [DOI] [PubMed] [Google Scholar]
- Mather H. M., Nisbet J. A., Burton G. H., Poston G. J., Bland J. M., Bailey P. A., Pilkington T. R. Hypomagnesaemia in diabetes. Clin Chim Acta. 1979 Jul 16;95(2):235–242. doi: 10.1016/0009-8981(79)90364-4. [DOI] [PubMed] [Google Scholar]
- McNair P., Christensen M. S., Christiansen C., Madsbad S., Transbøl I. Renal hypomagnesaemia in human diabetes mellitus: its relation to glucose homeostasis. Eur J Clin Invest. 1982 Feb;12(1):81–85. doi: 10.1111/j.1365-2362.1982.tb00942.x. [DOI] [PubMed] [Google Scholar]
- McNair P., Christiansen C., Madsbad S., Lauritzen E., Faber O., Binder C., Transbøl I. Hypomagnesemia, a risk factor in diabetic retinopathy. Diabetes. 1978 Nov;27(11):1075–1077. doi: 10.2337/diab.27.11.1075. [DOI] [PubMed] [Google Scholar]
- Moles K. W., McMullen J. K. Insulin resistance and hypomagnesaemia: case report. Br Med J (Clin Res Ed) 1982 Jul 24;285(6337):262–262. doi: 10.1136/bmj.285.6337.262. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ratzmann G. W. On the insulin effect on the magnesium homeostasis. Exp Clin Endocrinol. 1985 Dec;86(2):141–145. doi: 10.1055/s-0029-1210479. [DOI] [PubMed] [Google Scholar]
- STUTZMAN F. L., AMATUZIO D. S. Blood serum magnesium in portal cirrhosis and diabetes mellitus. J Lab Clin Med. 1953 Feb;41(2):215–219. [PubMed] [Google Scholar]
- Vanroelen W. F., Van Gaal L. F., Van Rooy P. E., De Leeuw I. H. Serum and erythrocyte magnesium levels in type I and type II diabetics. Acta Diabetol Lat. 1985 Jul-Sep;22(3):185–190. doi: 10.1007/BF02590769. [DOI] [PubMed] [Google Scholar]
- Weber B., Burger W., Hartmann R., Hövener G., Malchus R., Oberdisse U. Risk factors for the development of retinopathy in children and adolescents with type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 1986 Jan;29(1):23–29. doi: 10.1007/BF02427276. [DOI] [PubMed] [Google Scholar]