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. 1987 Mar;40(3):307–311. doi: 10.1136/jcp.40.3.307

Expression of c-myc oncogene in coeliac disease.

P J Ciclitira, J Stewart, G Evan, D G Wight, K Sikora
PMCID: PMC1140905  PMID: 3549790

Abstract

A monoclonal antibody, produced by peptide immunisation was used to detect the distribution of p62c/myc by immunohistology in normal and coeliac small intestinal mucosa. The effect of gluten in four treated coeliac patients was investigated by taking serial jejunal biopsy specimens for six hours after a 10 g oral gluten challenge. There was a progressive increase in p62c/myc staining intensity in the villus enterocytes extending to the crypts, which accompanied the classical morphological changes occurring in the mucosa.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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