Abstract
The clinical and pathological features of nine cases of granulomatous mastitis were compared with those of 10 cases of duct ectasia/periductal mastitis (DE/PM), all of which were associated with active granulomatous inflammation. Granulomatous mastitis affects a younger age group, and although there is some overlap with DE/PM, it has distinctive pathological features, particularly a lobule centred distribution, for which the term "granulomatous lobular mastitis" is recommended. There is a strong tendency for persistence or recurrence. Our cases of granulomatous mastitis all occurred in parous women, five of them within three years of pregnancy. Awareness of this condition is important, because surgery does not offer the best treatment of recurrent disease, and trials of adequate drug treatment, including corticosteroids, are required.
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- Banik S., Bishop P. W., Ormerod L. P., O'Brien T. E. Sarcoidosis of the breast. J Clin Pathol. 1986 Apr;39(4):446–448. doi: 10.1136/jcp.39.4.446. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bundred N. J., Dixon J. M., Lumsden A. B., Radford D., Hood J., Miles R. S., Chetty U., Forrest A. P. Are the lesions of duct ectasia sterile? Br J Surg. 1985 Oct;72(10):844–845. doi: 10.1002/bjs.1800721023. [DOI] [PubMed] [Google Scholar]
- Carmalt H. L., Ramsey-Stewart G. Granulomatous mastitis. Med J Aust. 1981 Apr 4;1(7):356–359. doi: 10.5694/j.1326-5377.1981.tb135631.x. [DOI] [PubMed] [Google Scholar]
- Cohen C. Granulomatous mastitis. A review of 5 cases. S Afr Med J. 1977 Jul 2;52(1):14–16. [PubMed] [Google Scholar]
- Davies J. D., Burton P. A. Postpartum lobular granulomatous mastitis. J Clin Pathol. 1983 Mar;36(3):363–363. doi: 10.1136/jcp.36.3.363-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DeHertogh D. A., Rossof A. H., Harris A. A., Economou S. G. Prednisone management of granulomatous mastitis. N Engl J Med. 1980 Oct 2;303(14):799–800. doi: 10.1056/NEJM198010023031406. [DOI] [PubMed] [Google Scholar]
- Dixon J. M., Anderson T. J., Lumsden A. B., Elton R. A., Roberts M. M., Forrest A. P. Mammary duct ectasia. Br J Surg. 1983 Oct;70(10):601–603. doi: 10.1002/bjs.1800701011. [DOI] [PubMed] [Google Scholar]
- Fletcher A., Magrath I. M., Riddell R. H., Talbot I. C. Granulomatous mastitis: a report of seven cases. J Clin Pathol. 1982 Sep;35(9):941–945. doi: 10.1136/jcp.35.9.941. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kessler E., Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol. 1972 Dec;58(6):642–646. doi: 10.1093/ajcp/58.6.642. [DOI] [PubMed] [Google Scholar]
- Koelmeyer T. D., MacCormick D. E. Granulomatous mastitis. Aust N Z J Surg. 1976 May;46(2):173–176. doi: 10.1111/j.1445-2197.1976.tb03227.x. [DOI] [PubMed] [Google Scholar]
- Miles R. S., Hood J., Bundred N. J., Jeffrey R. J., Davies G. C., Collee J. G. The role of Robertson's cooked-meat broth in the bacteriological evaluation of surgical specimens. J Med Microbiol. 1985 Dec;20(3):373–378. doi: 10.1099/00222615-20-3-373. [DOI] [PubMed] [Google Scholar]
- Milward T. M., Gough M. H. Granulomatous lesions in the breast presenting as carcinoma. Surg Gynecol Obstet. 1970 Mar;130(3):478–482. [PubMed] [Google Scholar]
- Rowe P. H. Granulomatous mastitis associated with a pituitary prolactinoma. Br J Clin Pract. 1984 Jan;38(1):32–34. [PubMed] [Google Scholar]
- Studdy P. R., Lapworth R., Bird R. Angiotensin-converting enzyme and its clinical significance--a review. J Clin Pathol. 1983 Aug;36(8):938–947. doi: 10.1136/jcp.36.8.938. [DOI] [PMC free article] [PubMed] [Google Scholar]