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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1987 Aug;40(8):909–913. doi: 10.1136/jcp.40.8.909

Some long term effects of smoking on the haemostatic system: a report from the Caerphilly and Speedwell Collaborative Surveys.

J W Yarnell 1, P M Sweetnam 1, S Rogers 1, P C Elwood 1, D Bainton 1, I A Baker 1, R Eastham 1, J R O'Brien 1, M D Etherington 1
PMCID: PMC1141135  PMID: 3654991

Abstract

Data from two community studies on men from South Wales and the west of England suggest that the effects of smoking on the haemostatic system remain for many years after giving up. Long term correlations between several variables, including plasma fibrinogen and white cell count, and the length of time after giving up were seen in ex-smokers. Dose response relations were apparent in current smokers in terms of the white cell count and two haematological variables, the packed and mean cell volumes. These long term correlations probably reflect the toxicity of other agents in tobacco smoke besides nicotine and carbon monoxide, which act only in the short term. Identification of these agents may further our understanding of the mechanism by which cigarette smoking is associated with atherosclerotic disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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