Abstract
The findings of a survey on the use of immunohistochemistry in district general hospitals in England and Wales are reported. Immunohistochemistry is used in most district hospitals, contributes to the accuracy and objectivity of some histopathological diagnoses, and is considered to be generally useful though not without drawbacks. Its expansion is being hindered by lack of funds for reagents and staff. In a few regions attempts are being made to rationalise expenditure and coordinate development of the service. We believe that if this can be done at a regional or national level then the relatively small cost entailed will be justified by a resulting improvement in the quality of patient care.
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Selected References
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- Gatter K. C., Alcock C., Heryet A., Mason D. Y. Clinical importance of analysing malignant tumours of uncertain origin with immunohistological techniques. Lancet. 1985 Jun 8;1(8441):1302–1305. doi: 10.1016/s0140-6736(85)92794-1. [DOI] [PubMed] [Google Scholar]
- Gatter K. C., Dunnill M. S., Van Muijen G. N., Mason D. Y. Human lung tumours may coexpress different classes of intermediate filaments. J Clin Pathol. 1986 Sep;39(9):950–954. doi: 10.1136/jcp.39.9.950. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ghosh A. K., Gatter K. C., Dunnill M. S., Mason D. Y. Immunohistological staining of reactive mesothelium, mesothelioma, and lung carcinoma with a panel of monoclonal antibodies. J Clin Pathol. 1987 Jan;40(1):19–25. doi: 10.1136/jcp.40.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Köhler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975 Aug 7;256(5517):495–497. doi: 10.1038/256495a0. [DOI] [PubMed] [Google Scholar]